EZR
-
Official Full Name
EZR ezrin -
Synonyms
EZR;ezrin;VIL2, villin 2 (ezrin);cytovillin 2;p81;villin-2;villin 2 (ezrin);CVL;CVIL;VIL2;MGC1584;FLJ26216;DKFZp762H157
Recombinant Proteins
- Human
- Rat
- Mouse
- Chicken
- Zebrafish
- E.coli
- HEK293
- Mammalian Cells
- Wheat Germ
- Yeast
- In Vitro Cell Free System
- His
- DDK
- Myc
- GST
- Non
- Flag
- Avi
- Fc
- SUMO
Involved Pathway
EZR involved in several pathways and played different roles in them. We selected most pathways EZR participated on our site, such as Leukocyte transendothelial migration,Regulation of actin cytoskeleton,Gastric acid secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with EZR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| MicroRNAs in cancer | ITGB3,NRAS,ERBB3,PIK3R2,TIMP3,NFKB1,PLAU,CCNG1,PIM1,MARCKS |
| Proteoglycans in cancer | ERBB3,CDC42,WNT4,PIK3CA,MSN,ITGB1,RPS6KB2,FZD7,PLCE1,MMP2 |
| Leukocyte transendothelial migration | ACTN1,PTPN11,MYLPF,NOX3,GNAI1,CLDN8,ICAM1,PIK3R3,CYBA,VASP |
| Gastric acid secretion | KCNE2,PRKCG,KCNK10,KCNJ2,PLCB4,CALM1,GNAI2,Slc4a2,ATP1A2,CA2 |
| Pathogenic Escherichia coli infection | NCK1,ARPC5L,TLR5,TUBB2B,CD14,TUBB2A,WAS,WASL,TUBB1,TUBA1A |
| Regulation of Actin Cytoskeleton | LIMK1A,FGF3,PDGFA,VCLA,ARHGEF7,GIT1,ITGA6B,PXNA,PAK6,F2 |
Protein Function
EZR has several biochemical functions, for example, ATPase binding,S100 protein binding,actin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by EZR itself. We selected most functions EZR had, and list some proteins which have the same functions with EZR. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| protein kinase A regulatory subunit binding | KCNQ1,ARFGEF1,PRKACA,AKAP1,RYR2,C2orf88,AKAP8,PJA2,ACBD3,AKAP9 |
| protein domain specific binding | ABCC2,HIST1H4F,ARL1,SKI,CHMP2B,HIST4H4,ODF1,FOXH1,VRK2,FOXA1 |
| S100 protein binding | ANXA2,FGF1,S100A11,AHNAK,FGF1A,KCNK3,S100B,DDX1,S100A6,AGER |
| ATPase binding | NSFL1C,Ar,ZNHIT6,USP25,TOR1AIP2,SELS,UBXN1,FAM119A,METTL21A,DRD1 |
| actin binding | WASLB,VMHCL,SYNE2,SYNE1,KLHL2,VCL,LSP1,INO80,SCINLA,GMFB |
| cell adhesion molecule binding | TENM2,SMAGP,PVRL3,CADM2A,CADM4,ITGA4,CD200,CADM3,NLGN3,ITGB3 |
| microtubule binding | KIF4,REEP4,REEP1,KIF1B,GABARAP,MACF1,RCC2,KIF25,SKA1,KIF27 |
| poly(A) RNA binding | RPSA,PRR3,DDX52,RC3H2,PEBP1,RPS25,PARP1,QK,PABPC1,CLNS1A |
| protein kinase A catalytic subunit binding | PRKAR2A,PJA2,PRKAR1B,PRKAR2B,GSK3B,PRKAR1A,CSK,KCNQ1,GSK3A,PKIA |
Interacting Protein
EZR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with EZR here. Most of them are supplied by our site. Hope this information will be useful for your research of EZR.
FES;MCC;SLC9A3R1;RDX;MDM2;1-phosphatidyl-1d-myo-inositol 3,5-bisphosphate
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