Fzd10 Protein


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Official Full Name frizzled class receptor 10
Background This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq, Jul 2008]
Synonyms FZD10; frizzled class receptor 10; Fz10; FzE7; CD350; FZ-10; hFz10; frizzled-10; frizzled homolog 10; frizzled family receptor 10; frizzled 10, seven transmembrane spanning receptor; Mfz10; Mfz10a; AL033370; AW456835
    • Species :
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • Human Cell
    • Mammalian Cell
    • Mammalian cells
    • Wheat Germ
    • Tag :
    • Fc
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human FZD10-2184H Recombinant Human FZD10 protein, His-tagged E. coli His
    Human FZD10-13064H Recombinant Human FZD10, GST-tagged E.coli GST
    Human FZD10-283H Recombinant Human FZD10, Fc-tagged Human Cell Fc
    Human FZD10-284H Recombinant Human FZD10, His-tagged Human Cell His
    Human FZD10-4589H Recombinant Human FZD10 Protein Wheat Germ N/A
    Human FZD10-4590H Recombinant Human FZD10 Protein, GST-tagged Wheat Germ GST
    Human FZD10-581H Recombinant Human Frizzled Family Receptor 10, Fc-tagged Mammalian cells Fc
    Mouse FZD10-2118MCL Recombinant Mouse FZD10 cell lysate Human Cell N/A
    Mouse Fzd10-276M Recombinant Mouse Fzd10 protein, Fc-tagged Mammalian cells Fc
    Mouse Fzd10-4042M Recombinant Mouse Fzd10, Fc tagged Human Cell Fc
    Mouse Fzd10-4043M Recombinant Mouse Fzd10, His tagged Human Cell His
    Chicken FZD10-5674C Recombinant Chicken FZD10 Mammalian Cell His
    Zebrafish FZD10-8558Z Recombinant Zebrafish FZD10 Mammalian Cell His

    Fzd10 involved in several pathways and played different roles in them. We selected most pathways Fzd10 participated on our site, such as Basal cell carcinoma, Class B/2 (Secretin family receptors), GPCR ligand binding, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fzd10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Basal cell carcinoma FZD6; WNT16; FZD5; Shh; HHIP; SETD6; FZD7; LEF1; WNT11; WNT8B
    Class B/2 (Secretin family receptors) ADM; CRHR1; SCT; PTHRP2; EMR1; SETD6; FZD10; GNB3A; ADCYAP1R1; RCA2.1
    GPCR ligand binding EMR2; EMR3; CCR8; EDNRA; PYY; NPS; CALCB; KEL; RAMP3; GPR37B
    Hippo signaling pathway BBC3; WNT5B; LIMD1; YWHAG; TGFB3; BMP6; YWHAE; WNT2; GDF5; SOX2
    Melanogenesis KITA; PRKCBA; a; WNT4A; ADCY1B; PRKCG; CALM2A; DCT; WNT2; ADCY1A
    Pathways in cancer GNA12; VEGFB; PRKCA; PTCH2; IKBKG; FZD3; RUNX1; SMO; WNT7B; PRKACG
    Proteoglycans in cancer ITGA2; DROSHA; SLC9A1; SDC4; SMO; TRP53; WNT10B; HRAS; PIK3R5; WNT2

    Fzd10 has several biochemical functions, for example, G-protein coupled receptor activity, Wnt-activated receptor activity, Wnt-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Fzd10 itself. We selected most functions Fzd10 had, and list some proteins which have the same functions with Fzd10. You can find most of the proteins on our site.

    Function Related Protein
    G-protein coupled receptor activity TAAR14F; TAAR7F; OPN1SW; OR2A4; GPR15; F2R; FZD3B; RHO; P2RY6; VIPR1B
    Wnt-activated receptor activity FZD7B; Fzd4; FZD5; FZD10; FZD3B; FZD9B; FZD6; LRP5L; FZD2; FZD8B
    Wnt-protein binding ROR2; FZD8; FZD1; FZD9; ROR1; FZD8B; FZD8A; LRP2A; FZD3B; FZD3
    protein binding GBP2; ARMC1; RAB1B; LMO4; MUTED; LPAR1; SEC61B; CRYBA1; GZMA; ITM2A

    Fzd10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fzd10 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fzd10.


    Gong, C; Qu, SH; et al. BRMS1L suppresses breast cancer metastasis by inducing epigenetic silence of FZD10. NATURE COMMUNICATIONS 5:-(2014).
    Sun, Q; Wang, RH; et al. Notch1 promotes hepatitis B virus X protein-induced hepatocarcinogenesis via Wnt/beta-catenin pathway. INTERNATIONAL JOURNAL OF ONCOLOGY 45:1638-1648(2014).

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