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  • Official Full Name

    frizzled class receptor 10

  • Overview

    This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq, Jul 2008]
  • Synonyms

    FZD10; frizzled class receptor 10; Fz10; FzE7; CD350; FZ-10; hFz10; frizzled-10; frizzled homolog 10; frizzled family receptor 10; frizzled 10, seven transmembrane spanning receptor; Mfz10; Mfz10a; AL033370; AW456835;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Chicken
  • Gallus gallus (Chicken)
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Zebrafish
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • Human Cell
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • Fc
  • hFc
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human FZD10-581H Active Recombinant Human Frizzled Family Receptor 10, Fc-tagged Mammalian cells Fc
Human FZD10-293H Active Recombinant Human FZD10 Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human FZD10-283H Recombinant Human FZD10, Fc-tagged Human Cell Fc Met1-Gly161
Human FZD10-13064H Recombinant Human FZD10, GST-tagged E.coli GST 23-229a.a.
Human FZD10-284H Recombinant Human FZD10, His-tagged Human Cell His Met1-Gly161
Human FZD10-4590H Recombinant Human FZD10 Protein, GST-tagged Wheat Germ GST
Human FZD10-4589H Recombinant Human FZD10 Protein Wheat Germ N/A
Human FZD10-3969H Recombinant Human FZD10 Protein (Met1-Gly161), C-Fc tagged Mammalian cells C-Fc Met1-Gly161
Human FZD10-1471H Recombinant Human FZD10 protein, His-tagged HEK293 His Ile21-Gly161
Human FZD10-5069HF Recombinant Full Length Human FZD10 Protein In Vitro Cell Free System 471 amino acids
Human FZD10-79H Recombinant Human FZD10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human FZD10-2184H Recombinant Human FZD10 protein, His-tagged E. coli His 23-229 aa
Human FZD10-79H-B Recombinant Human FZD10 Protein Pre-coupled Magnetic Beads HEK293
Mouse Fzd10-276M Active Recombinant Mouse Fzd10 protein, Fc-tagged Mammalian cells Fc
Mouse Fzd10-4042M Recombinant Mouse Fzd10 protein(Met1-Gly162), hFc-tagged HEK293 C-hFc Met1-Gly162
Mouse Fzd10-4043M Recombinant Mouse Fzd10, His tagged Human Cell His
Mouse FZD10-2118MCL Recombinant Mouse FZD10 cell lysate Human Cell N/A
Mouse Fzd10-52M Recombinant Mouse Fzd10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Fzd10-1539M Recombinant Mouse Fzd10 Protein, His-tagged E.coli N-His Trp235-Met495
Mouse Fzd10-52M-B Recombinant Mouse Fzd10 Protein Pre-coupled Magnetic Beads HEK293
Gallus gallus (Chicken) RFL2290GF Recombinant Full Length Chicken Frizzled-10(Fzd10) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (25-585)
Homo sapiens (Human) RFL11730HF Recombinant Full Length Human Frizzled-10(Fzd10) Protein, His-Tagged E.coli expression system His Full Length (21-581)
Mus musculus (Mouse) RFL31518MF Recombinant Full Length Mouse Frizzled-10(Fzd10) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (22-582)
Zebrafish FZD10-8558Z Recombinant Zebrafish FZD10 Mammalian Cell His
Chicken FZD10-5674C Recombinant Chicken FZD10 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Fzd10 Related Articles
  • Fzd10 Related Gene Family
  • Fzd10 Related Research Area
  • Fzd10 Related Signal Pathway

Fzd10 involved in several pathways and played different roles in them. We selected most pathways Fzd10 participated on our site, such as Basal cell carcinoma, Class B/2 (Secretin family receptors), GPCR ligand binding, which may be useful for your reference. Also, other proteins which involved in the same pathway with Fzd10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Basal cell carcinomaFZD1;WNT8B;WNT4;WNT3A;LEF1;AXIN1;TCF7;TRP53;WNT7B
Class B/2 (Secretin family receptors)CRHR1;RAMP3;GCGA;SCT;EMR2;ADCYAP1R1;GNB5A;PTHRP2;PTH2
Hippo signaling pathwaySCRIB;PRKCI;PARD6A;WNT16;TGFBR1;TP73;SMAD1;YAP1;YWHAZ
Proteoglycans in cancerTWIST1;WNT1;SDC4;PTK2;WNT9B;HSPB2;ROCK1;ITGAV;ELK1

Fzd10 has several biochemical functions, for example, G-protein coupled receptor activity, Wnt-activated receptor activity, Wnt-protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Fzd10 itself. We selected most functions Fzd10 had, and list some proteins which have the same functions with Fzd10. You can find most of the proteins on our site.

Function Related Protein
G-protein coupled receptor activityTAS2R143;GPR179;RPA1;GPR151;GPR26;S1PR3;FZD7;GPR132B;OLFCG2
Wnt-activated receptor activityFZD10;FZD7A;FZD2;Fzd4;LRP5L;FZD8B;FZD9B;FZD5;FZD8A
Wnt-protein bindingSMO;FZD5;FZD7;FRZB;FZD9;FZD2;FZD6;SFRP4;EVLA
protein bindingZBTB22;USP44;ZBTB9;SNX9;CSGALNACT2;MED14;DEPDC6;CD84;RGS14

Fzd10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Fzd10 here. Most of them are supplied by our site. Hope this information will be useful for your research of Fzd10.


Gong, C; Qu, SH; et al. BRMS1L suppresses breast cancer metastasis by inducing epigenetic silence of FZD10. NATURE COMMUNICATIONS 5:-(2014).
Sun, Q; Wang, RH; et al. Notch1 promotes hepatitis B virus X protein-induced hepatocarcinogenesis via Wnt/beta-catenin pathway. INTERNATIONAL JOURNAL OF ONCOLOGY 45:1638-1648(2014).
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