Recombinant Human FZD10 Protein

• Cat.No.: FZD10-4589H
• Product Overview: Human FZD10 full-length ORF (AAH70037.1) recombinant protein without tag.

Specification

• Description: This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer. [provided by RefSeq
• Source: Wheat Germ
• Species: Human
• Form: Liquid
• Molecular Mass: 65.4 kDa
• AA Sequence: MQRPGPRLWLVLQVMGSCAAISSMD MERPGDGKCQPIEIPMCKDIGYNMT RMPNLMGHENQREAVIQLHEFAPLV EYGCHGHLRFFLCSLYAPMCTEQVS TPIPACRVMCEQARLKCSPIMEQFN FKWPDSLDCRKLPNKNDPNYLCMEA PNNGSDEPTRGSGLFPPLFRPQRPH SAQEHPLKDGGPGRGGCDNPGKFHH VEKSASCAPLCTPGVDVYWSREDKR FAVVWLAIWAVLCFFSSAFTVLTFL IDPARFRYPERPIIFLSMCYCVYSV GYLIRLFAGAESIACDRDSGQLYVI QEGLESTGCTLVFLVLYYFGMASSL WWVVLTLTWFLAAGKKWGHEAIEAN SSYFHLAAWAIPAVKTILILVMRRV AGDELTGVCYVGSMDVNALTGFVLI PLACYLVIGTSFILSGFVALFHIRR VMKTGGENTDKLEKLMVRIGLFSVL YTVPATCVIACYFYERLNMDYWKIL AAQHKCKMNNQTKTLDCLMAASIPA VEIFMVKIFMLLVVGITSGMWIWTS KTLQSWQQVCSRRLKKKSRRKPASV ITSGGIYKKAQHPQKTHHGKYEIPA QSPTCV
• Applications: Antibody Production
  Functional Study
  Compound Screening
• Usage: Heating may cause protein aggregation. Please do not heat this product before electrophoresis.
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 25 mM Tris-HCl of pH8.0 containing 2% glycerol.

Gene Information

• Gene Name: FZD10 frizzled family receptor 10 [ Homo sapiens ]
• Official Symbol: FZD10
• Synonyms: FZD10; frizzled family receptor 10; frizzled (Drosophila) homolog 10, frizzled 10, seven transmembrane spanning receptor, frizzled homolog 10 (Drosophila); frizzled-10; CD350; frizzled homolog 10; frizzled 10, seven transmembrane spanning receptor; Fz10; FzE7; FZ-10; hFz10
• Gene ID: 11211
• mRNA Refseq: NM_007197
• Protein Refseq: NP_009128
• MIM: 606147
• UniProt ID: Q9ULW2