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GCGR

  • Official Full Name

    glucagon receptor

  • Overview

    The protein encoded by this gene is a glucagon receptor that is important in controlling blood glucose levels. Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM).
  • Synonyms

    GCGR; glucagon receptor; GGR; GL R; GL-R; GLR; GLR_HUMAN; Glucagon receptor precursor; MGC138246;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Rat
  • Rattus norvegicus (Rat)
  • CHO
  • E.coli
  • E.coli expression system
  • HEK293
  • In vitro E. coli expression system
  • Insect Cell
  • Mammalian Cell
  • Yeast
  • Fc
  • GST
  • hFc
  • His
  • His (Fc)
  • Avi
  • Myc
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human GCGR-0097H Active Recombinant Human GCGR Full Length Transmembrane protein(VLPs) HEK293 N/A Ala 26 - Asn 432
Human GCGR-0947H Active Recombinant Human GCGR Full Length Transmembrane protein(Nanodisc) HEK293 N/A
Human GCGR-5989HCL Recombinant Human GCGR 293 Cell Lysate HEK293 N/A
Human GCGR-2219H Recombinant Human GCGR protein, His&Myc-tagged Insect Cell His&Myc 26-136aa
Human GCGR-1495H Active Recombinant Human GCGR protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Ala26-Lys136
Human GCGR-001H Recombinant Human GCGR Protein, His-tagged E.coli His
Human GCGR-1571H Recombinant Human GCGR Protein, His&GST-tagged E.coli N-His&GST Ala26-Met137
Human GCGR-5014H Recombinant Human GCGR protein, His&Myc-tagged HEK293 His&Myc 26-136aa
Human GCGR-2951H Recombinant Human GCGR protein, His&Myc-tagged E.coli His&Myc 26-136aa
Human GCGR-1493H Recombinant Human GCGR protein, hFc-tagged HEK293 hFc Ala26-Lys136
Human GCGR-2107H Recombinant Human GCGR protein, His-tagged HEK293 His Ala 26 - Lys 136
Human GCGR-5413H Recombinant Human GCGR protein, His-tagged Yeast His 26-136aa
Human GCGR-1319H Recombinant Human GCGR Full Length Transmembrane protein, His-tagged In vitro E. coli expression system His 26-477aa
Human GCGR-1494H Active Recombinant Human GCGR protein, Fc-tagged CHO Fc Ala26-Lys136
Mouse GCGR-518M Recombinant Mouse GCGR Protein (27-143 aa), GST-tagged E.coli GST 27-143 aa
Mouse GCGR-2206M Recombinant Mouse GCGR protein, Fc-tagged HEK293 Fc Ala 27 - Lys 137
Mouse GCGR-2338M Recombinant Mouse GCGR Protein (27-143 aa), His-tagged Yeast His 27-143 aa
Rat GCGR-2488R Recombinant Rat GCGR Protein Mammalian Cell His
Rat GCGR-2144R Recombinant Rat GCGR Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat GCGR-2144R-B Recombinant Rat GCGR Protein Pre-coupled Magnetic Beads HEK293
Homo sapiens (Human) RFL6HF Recombinant Full Length Human Glucagon Receptor(Gcgr) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (26-477)
Rattus norvegicus (Rat) RFL33811RF Recombinant Full Length Rat Glucagon Receptor(Gcgr) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (27-485)
Kit-1253 GCGR CHO-K1 β-Arrestin-1 GPCR Assay Kit N/A
Kit-1027 Phospho-ERK1/2 (Thr202/Tyr204) Translocation Assay Kit (Cell-Based) N/A
Kit-1250 GCGR CHO-K1 β-Arrestin GPCR Assay Kit N/A
Kit-1249 GCGR Total GPCR Internalization Assay Kit N/A
Kit-1252 cAMP GCGR CHO-K1 GPCR Assay Kit N/A
Kit-1029 Total Collagen Assay Kit (Colorimetric) N/A
Kit-1251 CHO-K1 GCGR Bioassay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

GCGR involved in several pathways and played different roles in them. We selected most pathways GCGR participated on our site, such as Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with GCGR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Neuroactive ligand-receptor interactionLPAR4;TAAR1;GRIN2B;PTGER4B;TSHR;PTGDR;TAAR12H;P2RX4A;TAAR7D

GCGR has several biochemical functions, for example, guanyl-nucleotide exchange factor activity, peptide hormone binding. Some of the functions are cooperated with other proteins, some of the functions could acted by GCGR itself. We selected most functions GCGR had, and list some proteins which have the same functions with GCGR. You can find most of the proteins on our site.

Function Related Protein
guanyl-nucleotide exchange factor activityRAPGEFL1;PTGIR;GAPVD1;RALGPS1;ARHGEF1B;FLCN;TBXA2R;RAPGEF3;RASGEF1BA
peptide hormone bindingEDNRB;RXFP2;PRLR;AVPR1A;SLC40A1;GALR1;NPR1;GHR;PTH1R

GCGR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with GCGR here. Most of them are supplied by our site. Hope this information will be useful for your research of GCGR.

PSMD2; Hacd3; TGM2; TP63

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