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Official Full Name glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1)
Background Aspartate aminotransferase, cytoplasmic is an enzyme that in humans is encoded by the GOT1 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively.
Synonyms GOT1; glutamic-oxaloacetic transaminase 1, soluble (aspartate aminotransferase 1); aspartate aminotransferase, cytoplasmic; transaminase A; growth-inhibiting protein 18; glutamate oxaloacetate transaminase 1; GIG18; ASTQTL1
    • Species :
    • Cattle
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Porcine
    • Rat
    • Zebrafish
    • Source :
    • E.coli
    • E.Coli or Yeast
    • HEK293
    • HEK293T
    • Human Heart
    • Mammalian Cell
    • Porcine Heart
    • Wheat Germ
    • Yeast
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human GOT1 -154H Recombinant Human GOT1 Protein E.coli N/A
    Human GOT1-1495H Recombinant Human GOT1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human GOT1-27058TH Recombinant Human GOT1, His-tagged E.coli His
    Human GOT1-434H Recombinant Human GOT1 protein, His-tagged Yeast His
    Human GOT1-504H Recombinant Human GOT1, His tagged E.coli His
    Human GOT1-5126H Recombinant Human GOT1 Protein, GST-tagged Wheat Germ GST
    Human GOT1-5351H Native Human Glutamic-Oxaloacetic Transaminase 1, Soluble (aspartate aminotransferase 1) Human Heart N/A
    Human GOT1-5824HCL Recombinant Human GOT1 293 Cell Lysate HEK293 N/A
    Human GOT1-60H Recombinant Human GOT1 protein, His-tagged E.coli His
    Mouse Got1-1043M Recombinant Mouse Got1 Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Got1-3668M Recombinant Mouse Got1, His-tagged E.Coli or Yeast His
    Mouse Got1-65M Recombinant Mouse Got1, His-tagged E.coli His
    Mouse GOT1-7078M Recombinant Mouse GOT1 Protein Mammalian Cell His
    Mouse Got1-7214M Recombinant Mouse Got1 Protein, His-tagged E.coli His
    Rat GOT1-2623R Recombinant Rat GOT1 Protein Mammalian Cell His
    Rat Got1-5817R Recombinant Rat Got1 protein, His-tagged E.coli His
    Cynomolgus Monkey GOT1-557C Recombinant Cynomolgus GOT1 Protein, His-tagged Mammalian Cell His
    Chicken GOT1-6873C Recombinant Chicken GOT1 Mammalian Cell His
    Zebrafish GOT1-12290Z Recombinant Zebrafish GOT1 Mammalian Cell His
    Porcine GOT1-5353P Native Porcine GOT1 protein Porcine Heart N/A
    Cattle GOT1-5816C Recombinant Cattle GOT1 protein, His & T7-tagged E.coli His/T7

    got1 involved in several pathways and played different roles in them. We selected most pathways got1 participated on our site, such as Arginine biosynthesis, Alanine, aspartate and glutamate metabolism, Cysteine and methionine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with got1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Arginine biosynthesis GPT2L; GLUD2; ASL2; GLUD1A; GOT2B; GOT1; GOT2; GLULB; GLUL; GLS2
    Alanine, aspartate and glutamate metabolism GFPT2; GLULA; GFPT1; GOT1; ASPA; GLUD1B; GLULC; NIT2; CPS1; GLUD1
    Cysteine and methionine metabolism MAT1A; LDHA; GCLM; MTR; MDH1AA; AHCY; SDSL; GOT1; DNMT3AB; CBSA
    Arginine and proline metabolism L3HYPDH; NOS3; DAO.3; PRODH; SAT1; ALDH9A1; PYCRL; CKMA; GOT2B; LSM1
    Tyrosine metabolism HPDB; TH; COMTA; TPO; ALDH3B1; FAH; COMTB; MAOB; AOX3L1; HPDA
    Phenylalanine metabolism PAH; TAT; HPD; MAOA; MIF; AOC2; GM4952; ALDH3B1; GOT2A; MAOB
    Phenylalanine, tyrosine and tryptophan biosynthesis GOT2B; TAT; GOT2; GOT1; GOT2A; IL4I1; PAH
    Metabolic pathways COX5AA; CBS; GALNTL4; PFKMB; GALNT10; PGAM1A; GALNT13; TGDS; NDUFB4; CYP26C1
    Carbon metabolism ackA; PFKMA; GPR19; TALDO1; SUCLG2; TKTB; HADHA; MCEE; SDSL; SUCLA2
    -Oxocarboxylic acid metabolism IDH3A; GOT2B; BCAT2; GPT2L; IDH3B; IDH3G; IDH1; GPT2; GOT2; BCAT1
    Biosynthesis of amino acids ALDOCB; TPI1A; BCAT2; TKT; MAT2B; PFKP; NAGS; PKMB; PGK2; SDSL

    got1 has several biochemical functions, for example, L-aspartate:2-oxoglutarate aminotransferase activity, L-cysteine:2-oxoglutarate aminotransferase activity, L-phenylalanine:2-oxoglutarate aminotransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by got1 itself. We selected most functions got1 had, and list some proteins which have the same functions with got1. You can find most of the proteins on our site.

    Function Related Protein
    L-aspartate:2-oxoglutarate aminotransferase activity GOT1; GOT2; GOT2B; GOT1L1; GOT2A
    L-cysteine:2-oxoglutarate aminotransferase activity GOT1
    L-phenylalanine:2-oxoglutarate aminotransferase activity TAT; GOT2B; GOT1; GOT2A; GOT2
    carboxylic acid binding PCK1; AKR1C21; GRHPR; HMGCL; AKR1C2; HIF1AN; GOT1
    identical protein binding ACPP; SHANK3; TP73; IGF2R; TRIM8; NUP153; CD247; EWSR1; STXBP1; PRMT8
    phosphatidylserine decarboxylase activity GOT1; PISD
    pyridoxal phosphate binding ALAS2; PYGL; CBSA; SPTLC2; PYGM; NFS1; GCAT; PYGB; CBS; AGXT2L2

    got1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with got1 here. Most of them are supplied by our site. Hope this information will be useful for your research of got1.

    HLA-B; TNIK; EGFR; ABI3BP; TMEM120A; ere_dna

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