Active Native Human GOT1 Protein

• Cat.No.: GOT1-01H
• Product Overview: Native Human GOT1 Protein purified from human liver.
  CK: < 1.0 %
  ALT/GPT: < 2.0 %
  LDH: < 10 %
  Ammonia: < 0.01 micromole/mg
  UNSPSC code: 51131907
  CAS Number: 9000-97-9
  E.C. Number: 2.6.1.1

Specification

• Species: Human
• Source: Liver
• Tag: Non
• Description: Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.
• Form: Lyophilized
• Bio-activity: > 1 U/mg
• Molecular Mass: ~92 kDa (Feliss and martinez-Carrion 1970)
• Unit Definition: One unit will catalyze the transamination of one micromole of L-aspartate to alpha-ketoglutarate forming L-glutamate and oxaloacetate per minute at 37 centigrade and pH 7.8.
• Applications: Clinical Chemistry
• Storage: At -20 centigrade.
• Concentration: > 0.5 mg protein/mg (Coomassie)

Gene Information

• Gene Name: GOT1 glutamic-oxaloacetic transaminase 1 [ Homo sapiens (human) ]
• Official Symbol: GOT1
• Synonyms: GOT1; glutamic-oxaloacetic transaminase 1; AST; AST1; SGOT; cCAT; GIG18; cAspAT; ASTQTL1; aspartate aminotransferase, cytoplasmic; aspartate aminotransferase 1; aspartate transaminase 1; cysteine aminotransferase, cytoplasmic; cysteine transaminase, cytoplasmic; glutamate oxaloacetate transaminase 1; glutamic-oxaloacetic transaminase 1, soluble; growth-inhibiting protein 18; testis secretory sperm-binding protein Li 196a; transaminase A; EC 2.6.1.1; EC 2.6.1.3
• Gene ID: 2805
• mRNA Refseq: NM_002079
• Protein Refseq: NP_002070
• MIM: 138180
• UniProt ID: P17174