| Cat.No. : |
HSPB1-070H |
| Product Overview : |
Recombinant N-terminally Histidine-tagged full length human Hsp27 protein (2-205) was purified from E. coli. |
| Description : |
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy. |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
His |
| Molecular Mass : |
25.5 kDa |
| Protein length : |
2-205 |
| Purity : |
≥90% as determined by SDS-PAGE |
| Stability : |
≥ 2 years |
| Storage : |
At -80 centigrade. |
| Storage Buffer : |
50 mM Tris HCl, pH 7.5, 150 mM sodium chloride, 1mM DTT, 20% glycerol |
| SDS-PAGE analysis of Hsp27 : |
Lane 1: MW Markers
Lane 2: Hsp27 (1 μg)
Lane 3: Hsp27 (2 μg)
Lane 4: Hsp27 (4 μg)
|
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.