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Official Full Name interleukin 11 receptor, alpha
Background Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus, and three variants encoding two different isoforms have been identified.
Synonyms IL11RA; interleukin 11 receptor, alpha; interleukin-11 receptor subunit alpha; hCG_2011440; I11RA_HUMAN; IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA; Interleukin 11 receptor alpha; MGC2146; OTTHUMP00000021300; OTTHUMP00000021301; OTTHUMP00000244525; OTTHUMP00000244527; OTTHUMP00000244532; interleukin-11 receptor alpha chain; CRSDA
    • Species :
    • Canine
    • Chicken
    • Human
    • Mouse
    • Zebrafish
    • Source :
    • E. coli
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • Tag :
    • Fc
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human IL11RA-1328H Recombinant Human IL11RA protein, His-tagged E.coli His
    Human IL11RA-2389HCL Recombinant Human IL11RA cell lysate Human Cell N/A
    Human IL11RA-3155H Recombinant Human IL11RA, His tagged Human Cell His
    Human IL11RA-561H Recombinant Human IL11RA Protien, GST-tagged E. coli GST
    Mouse IL11RA-2558MCL Recombinant Mouse IL11RA cell lysate Human Cell N/A
    Canine IL11RA-001CCL Recombinant Canine IL11RA cell lysate Human Cell N/A
    Canine IL11RA-1046C Recombinant Canine IL11RA Protein, Fc-tagged HEK293 Fc
    Canine IL11RA-173C Recombinant Canine IL11RA, His-tagged Human Cell His
    Canine IL11RA-174C Recombinant Canine IL11RA, LEVLFQ tagged Human Cell His
    Chicken IL11RA-3466C Recombinant Chicken IL11RA Mammalian Cell His
    Zebrafish IL11RA-6298Z Recombinant Zebrafish IL11RA Mammalian Cell His

    il11ra involved in several pathways and played different roles in them. We selected most pathways il11ra participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with il11ra were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interaction LIFR; PF4; TNFRSF11A; BMPR1AB; CXCL12B; IL5; PDGFRB; KITA; IFNAR2; BMPR1BB
    Jak-STAT signaling pathway MTOR; IL21; RNF207B; RAF1B; STAM2; AKT2L; LIF; TSLP; IFNG1-2; RAF1
    Hematopoietic cell lineage IL2RA; CSF1; IL3RA; HLA-DRB3; CD3E; CD4; CR1; CD36; Itgam&Itgb2; CD19

    il11ra has several biochemical functions, for example, cytokine receptor activity, signal transducer activity, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by il11ra itself. We selected most functions il11ra had, and list some proteins which have the same functions with il11ra. You can find most of the proteins on our site.

    Function Related Protein
    cytokine receptor activity IL2RGA; Ifnlr1; IL21R.2; IL20RB; IRX1; CRFB16; IL12RB1; IL12RB2; PRLRA; CSF3R
    signal transducer activity NPY8AR; MGAA; GPR15; GNGT2B; AVP; GNA15.1; BCAR1; DRD4-RS; OPN1SW2; OLFR49
    transmembrane signaling receptor activity SIGLEC8; P2RX6; LGR4; ANTXR1; OR115-6; PTH1RA; GHRHRL; KIR2DL4; FZD7B; TLR9

    il11ra has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with il11ra here. Most of them are supplied by our site. Hope this information will be useful for your research of il11ra.


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