|Official Full Name||interleukin 11 receptor, alpha|
|Background||Interleukin 11 is a stromal cell-derived cytokine that belongs to a family of pleiotropic and redundant cytokines that use the gp130 transducing subunit in their high affinity receptors. This gene encodes the IL-11 receptor, which is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus, and three variants encoding two different isoforms have been identified.|
|Synonyms||IL11RA; interleukin 11 receptor, alpha; interleukin-11 receptor subunit alpha; hCG_2011440; I11RA_HUMAN; IL-11 receptor subunit alpha; IL-11R subunit alpha; IL-11R-alpha; IL-11RA; Interleukin 11 receptor alpha; MGC2146; OTTHUMP00000021300; OTTHUMP00000021301; OTTHUMP00000244525; OTTHUMP00000244527; OTTHUMP00000244532; interleukin-11 receptor alpha chain; CRSDA|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
il11ra involved in several pathways and played different roles in them. We selected most pathways il11ra participated on our site, such as Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway, Hematopoietic cell lineage, which may be useful for your reference. Also, other proteins which involved in the same pathway with il11ra were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Cytokine-cytokine receptor interaction||LIFR; PF4; TNFRSF11A; BMPR1AB; CXCL12B; IL5; PDGFRB; KITA; IFNAR2; BMPR1BB|
|Jak-STAT signaling pathway||MTOR; IL21; RNF207B; RAF1B; STAM2; AKT2L; LIF; TSLP; IFNG1-2; RAF1|
|Hematopoietic cell lineage||IL2RA; CSF1; IL3RA; HLA-DRB3; CD3E; CD4; CR1; CD36; Itgam&Itgb2; CD19|
il11ra has several biochemical functions, for example, cytokine receptor activity, signal transducer activity, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by il11ra itself. We selected most functions il11ra had, and list some proteins which have the same functions with il11ra. You can find most of the proteins on our site.
|cytokine receptor activity||IL2RGA; Ifnlr1; IL21R.2; IL20RB; IRX1; CRFB16; IL12RB1; IL12RB2; PRLRA; CSF3R|
|signal transducer activity||NPY8AR; MGAA; GPR15; GNGT2B; AVP; GNA15.1; BCAR1; DRD4-RS; OPN1SW2; OLFR49|
|transmembrane signaling receptor activity||SIGLEC8; P2RX6; LGR4; ANTXR1; OR115-6; PTH1RA; GHRHRL; KIR2DL4; FZD7B; TLR9|
il11ra has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with il11ra here. Most of them are supplied by our site. Hope this information will be useful for your research of il11ra.