• Official Full Name

    interleukin 2 receptor, gamma chain

  • Background

    CD132 is a 64-70 kD type I transmembrane glycoprotein of the Ig superfamily, also known as common gamma chain (gammac), or IL-2 receptor gamma subunit. It is expressed broadly on T- and B-lymphocytes, NK cells, monocytes, and granulocytes. CD132 is an ess
  • Synonyms

    IL2RG; interleukin 2 receptor, gamma chain; cytokine receptor common subunit gamma; p64; IL-2RG; gammaC; gamma C receptor; common gamma chain; IL-2R subunit gamma; IL-2 receptor subunit gamma; common cytokine receptor gamma chain; interleukin-2 receptor subunit gamma; gc; [g]c; CD132; gamma(c);
    • Type:
    • Recombinant Proteins
    • Cell & Tissue Lysates
    • Protein Pre-coupled Magnetic Beads
    • Species :
    • Chicken
    • Cynomolgus
    • Human
    • Mouse
    • Pig
    • Rat
    • Rhesus
    • Rhesus Macaque
    • Rhesus monkey
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Human Cells
    • Insect Cell
    • Mammalian Cell
    • Sf21 Insect Cell
    • Wheat Germ
    • Tag :
    • C
    • His
    • Fc
    • GST
    • GST|His
    • hFc
    • hIgG1
    • hIgG4
    • His (Fc)
    • Avi
    • human|IgG1|Fc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Chicken IL2RG-6096C Recombinant Chicken IL2RG Mammalian Cell His
    Cynomolgus IL2RG-382C Recombinant Cynomolgus IL2RG protein, His-tagged HEK293 His
    Cynomolgus IL2RG-0170C Recombinant Cynomolgus IL2RG protein, His-tagged HEK293 His
    Human IL2RG-29663TH Recombinant Human IL2RG, Fc-tagged Fc
    Human IL2RG-502HCL Recombinant Human IL2RG cell lysate Insect Cell N/A
    Human IL2RG-7066H Recombinant Human IL2RG protein, His-tagged E.coli His
    Human IL2RG-949H Recombinant Human IL2RG Protein, GST-His-tagged E.coli GST/His
    Human IL2RG-119H Recombinant Human IL2RG, Gamma, Fc Chimera HEK293 Fc
    Human IL2RG-7289H Recombinant Human IL2RG protein, Fc-tagged HEK293 human/IgG1/Fc
    Human IL2RG-5193H Recombinant Human IL2RG Protein, GST-tagged Wheat Germ GST
    Human IL2RG-0172H Recombinant Human IL2RG protein, Fc-tagged HEK293 Fc
    Human IL2RG-14197H Recombinant Human IL2RG Protein, GST-tagged E.coli GST
    Human IL2RG-49H Recombinant Human IL2RG, His-tagged Insect Cell His
    Human IL2RG-151H Recombinant Human IL2RG Protein, His-tagged Human Cells His
    Human IL2RG-2137H Recombinant Human IL2RG protein, His-tagged HEK293 His
    Human IL2RG-6963H Recombinant Human IL2RG, His tagged Insect Cell His
    Human IL2RG-5194H Recombinant Human IL2RG Protein Wheat Germ N/A
    Human IL2RG-54H Recombinant Human IL2RG Protein, GST-tagged E.coli GST
    Human IL2RG-895H Recombinant Human IL2RG protein, His-Avi-tagged, Biotinylated(VLPs) HEK293 His-Avi
    Human IL2RG-785H Recombinant Human IL2RG protein, His-Avi-tagged HEK293 His-Avi
    Human IL2RG-067H Recombinant Human IL2RG Protein, C-His-tagged E.coli C-His
    Human IL2RG-1350H Recombinant Human IL2RG protein, His-tagged HEK293 His
    Human IL2RG-323H Recombinant Human IL2RG Protein, Fc-tagged HEK293 Fc
    Human IL2RG-1481HCL Recombinant Human IL2RG cell lysate Human Cell N/A
    Mouse IL2RG-2908MCL Recombinant Mouse IL2RG cell lysate Human Cell N/A
    Mouse Il2rg-1716M Recombinant Mouse Interleukin 2 Receptor, Gamma Chain Sf21 Insect Cell N/A
    Mouse Il2rg-7067M Recombinant Mouse Il2rg protein, His-tagged E.coli His
    Mouse Il2rg-4005M Recombinant Mouse Il2rg, His tagged Human Cell His
    Mouse Il2rg-784M Recombinant Mouse Il2rg protein, His&hFc-tagged HEK293 His&hFc
    Mouse IL2RG-0169M Recombinant Mouse IL2RG protein, His-Avi-tagged, Biotinylated HEK293 His-Avi
    Mouse IL2RG-0171M Recombinant Mouse IL2RG protein, His-tagged HEK293 His
    Pig IL2RG-3369P Recombinant Pig IL2RG protein, His-tagged E.coli His
    Rat IL2RG-1476RCL Recombinant Rat IL2RG cell lysate Human Cell N/A
    Rat Il2rg-7456R Recombinant Rat Il2rg, Fc tagged Human Cell Fc
    Rat Il2rg-7457R Recombinant Rat Il2rg protein, His-tagged HEK293 His
    Rhesus IL2RG-228R Recombinant Rhesus IL2RG protein, His-tagged HEK293 His
    Rhesus IL2RG-034R Recombinant Rhesus IL2RG protein, hFc-tagged HEK293 hFc
    Rhesus Macaque IL2RG-2070R-B Recombinant Rhesus Macaque IL2RG Protein Pre-coupled Magnetic Beads HEK293
    Rhesus Macaque IL2RG-2249R Recombinant Rhesus monkey IL2RG Protein, His-tagged Mammalian Cell His
    Rhesus Macaque IL2RG-2070R Recombinant Rhesus Macaque IL2RG Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
    Rhesus monkey IL2RG-1563R Recombinant Rhesus Monkey IL2RG Protein, hIgG1-tagged HEK293 hIgG1
    Rhesus monkey IL2RG-1562R Recombinant Rhesus Monkey IL2RG Protein HEK293 N/A
    Rhesus monkey IL2RG-1564R Recombinant Rhesus Monkey IL2RG Protein, hIgG4-tagged HEK293 hIgG4
    • Involved Pathway
    • Protein Function
    • Interacting Protein
    • Il2rg Related Articles
    • Il2rg Related Gene Family
    • Il2rg Related Research Area
    • Il2rg Related Signal Pathway

    Il2rg involved in several pathways and played different roles in them. We selected most pathways Il2rg participated on our site, such as Cytokine-cytokine receptor interaction, Endocytosis, PIK-Akt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Il2rg were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Cytokine-cytokine receptor interactionIFNA4;EDA2R;IL8L2;GHR;CCL17;RELT;KITB;CXCL8;TNFRSF8
    PIK-Akt signaling pathwayKLK1B4;IRS1;PPP2R2B;FGF6;GYS1;TNC;CCND3;NGFR;GYS2
    Jak-STAT signaling pathwayIFNA7;RAF1A;MPL;PIAS4B;IL4R;IRX1;PIAS1;IFNK;IL21R.1
    Inflammatory bowel disease (IBD)IL18;Il4ra;IL12A;RORA;TGFB1;HLA-DRB5;IFNGR2;IL2RG;HLA-DOB
    Primary iRFX5;CD40;TAP1;UNG;TNFRSF13B;Cd79a, Cd79b;AICDA;RAG1;TAP2

    Il2rg has several biochemical functions, for example, interleukin-2 binding, contributes_to interleukin-2 receptor activity, contributes_to interleukin-4 receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Il2rg itself. We selected most functions Il2rg had, and list some proteins which have the same functions with Il2rg. You can find most of the proteins on our site.

    Function Related Protein
    interleukin-2 bindingIL2RG;IL2RB;IL2RA
    contributes_to interleukin-2 receptor activityIL2RB;IL2RG
    contributes_to interleukin-4 receptor activity
    interleukin-7 binding
    contributes_to interleukin-7 receptor activity
    protein bindingARL4A;RAP1A;DHX30;FTSJ3;HSPB1;LSM6;MBIP;FAT4;FOSL1

    Il2rg has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Il2rg here. Most of them are supplied by our site. Hope this information will be useful for your research of Il2rg.

    IL4; IL4R; NOTCH2NL; IL15RA; IL7; IL7R; GRB2

    Motobayashi, M; Inaba, Y; et al. Successful treatment for West syndrome with severe combined immunodeficiency. BRAIN & DEVELOPMENT 37:140-144(2015).
    Wan, SS; Zhao, ED; et al. Tumor-Associated Macrophages Produce Interleukin 6 and Signal via STAT3 to Promote Expansion of Human Hepatocellular Carcinoma Stem Cells. GASTROENTEROLOGY 147:1393-1404(2014).
    • Q&As
    • Reviews

    Q&As (6)

    Ask a question
    Are there any side effects of using this protein? 12/23/2022

    The use of IL2RG may cause chest tightness, skin itching, allergies and other side effects, you need to contact the doctor for timely treatment.

    What is the dosage and use method of IL2RG? 11/03/2022

    The dosage and use method of IL2RG need to be determined according to the condition and individual situation, and need to be prescribed by a clinician.

    Does IL2RG have a role and what is the mechanism? 11/28/2021

    Enhances the immunity of the human immune system by increasing the number and improving the function of immune cells in the body.

    Which diseases is IL2RG used to treat? 06/22/2021

    IL2RG is mainly used in the treatment of immune deficiency diseases, such as systemic eosinophilic granulomatosis, X-linked immunodeficiency disease, etc.

    What measures can be taken to mitigate the possible risks of IL2RG? 06/15/2021

    In view of possible risks, the use of IL2RG should be strictly in accordance with the doctor's advice, and avoid changing the dosage and frequency of medication.

    What are the pharmacological characteristics of IL2RG? 08/14/2019

    IL2RG pharmacological features are contained in vivo to enhance the immunity of the human immune system by increasing the number of immune cells and improving their function.

    Customer Reviews (3)

    Write a review

      Purity of IL2RG is tested to ensure that no impurities are present in the protein, and its binding capacity and signal transduction function to the corresponding ligand, such as IL-2, is verified by appropriate bioactivity experiments. -


        Solubility and stability of IL2RG under different solution conditions were investigated to ensure its stability during storage and use and its ability to maintain its biological activity. -


          To evaluate the stability of the three-dimensional structure of IL2RG, the structure of the protein and its changes can be studied by crystallography and nuclear magnetic resonance techniques. -

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