Recombinant Human IL2RG protein, His-Avi-tagged

• Cat.No.: IL2RG-785H
• Product Overview: Recombinant Human CD132 Protein is expressed from mammalian with His Tag and Avi Tag at the C-terminal. It contains Leu 23-Asn 254.

Specification

• Species: Human
• Source: HEK293
• Tag: Avi&His
• Protein Length: Leu 23-Asn 254
• Description: The gamma chain of the high affinity functional human IL-2 receptor complex belongs to the hematopoietin receptor family. IL-2 R gamma is a 369 amino acid residue protein consisting of a 22 residue signal sequence, a 232 residue extracellular domain, a 29 residue transmembrane domain and an 86 residue cytoplasmic domain. Although IL-2 R gamma by itself does not bind IL-2 with any appreciable affinity, it is required for IL-2 receptor signaling.
• Form: Supplied as 0.22um filtered solution in PBS (pH 7.4).
• Molecular Mass: The protein has a predicted MW of 39.9 KDa. Due to glycosylation, the protein migrates to 58- 70KDa based on Bis-Tris PAGE result.
• Endotoxin: Less than 0.2 EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.

Gene Information

• Gene Name: IL2RG interleukin 2 receptor subunit gamma [ Homo sapiens (human) ]
• Official Symbol: IL2RG
• Synonyms: CD132 antigen; CD132; CIDX; combined immunodeficiency, X-linked; common cytokine receptor gamma chain; Common gamma Chain; common gamma-chain; cytokine receptor common subunit gamma; gamma(c); IL-2 R gamma; IL-2 receptor subunit gamma; IL2R gamma; IL-2R subunit gamma; IL2RG; IL-2RG; IMD4; interleukin 2 receptor, gamma; Interleukin-2 receptor subunit gamma; P64; SCIDX; SCIDX1; severe combined immunodeficiency.
• Gene ID: 3561
• mRNA Refseq: NM_000206.3
• Protein Refseq: NP_000197.1
• MIM: 308380
• UniProt ID: P31785