Recombinant Human IL2RG Protein, GST-tagged

• Cat.No.: IL2RG-14197H
• Product Overview: Recombinant Human IL2RG Protein with a GST tag was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.
• Source: E. coli
• Species: Human
• Tag: GST
• Molecular Mass: ~ 66.2KDa, reducing conditions
• AA Sequence: MSPILGYWKIKGLVQPTRLLLEYLE EKYEEHLYERDEGDKWRNKKFELGL EFPNLPYYIDGDVKLTQSMAIIRYI ADKHNMLGGCPKERAEISMLEGAVL DIRYGVSRIAYSKDFETLKVDFLSK LPEMLKMFEDRLCHKTYLNGDHVTH PDFMLYDALDVVLYMDPMCLDAFPK LVCFKKRIEAIPQIDKYLKSSKYIA WPLQGWQATFGGGDHPPKSDLVPRG SLNTTILTPNGNEDTTADFFLTTMP TDSLSVSTLPLPEVQCFVFNVEYMN CTWNSSSEPQPTNLTLHYWYKNSDN DKVQKCSHYLFSEEITSGCQLQKKE IHLYQTFVVQLQDPREPRRQATQML KLQNLVIPWAPENLTLHKLSESQLE LNWNNRFLNHCLEHLVQYRTDWDHS WTEQSVDYRHKFSLPSVDGQKRYTF RVRSRFNPLCGSAQHWSEWSHPIHW GSNTSKENPFLFALEAVVISVGSMG LIISLLCVYFWLERTMPRIPTLKNL EDLVTEYHGNFSAWSGVSKGLAESL QPDYSERLCLVSEIPPKGGALGEGP GASPCNQHSPYWAPPCYTLKPET
• Purity: >90%, by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.1 mg/mL
• Storage Buffer: Supplied as a 0.2 μm filtered solution in PBS, pH 8.0

Gene Information

• Gene Name: IL2RG interleukin 2 receptor subunit gamma [ Homo sapiens (human) ]
• Official Symbol: IL2RG
• Synonyms: IL2RG; interleukin 2 receptor subunit gamma; P64; CIDX; IMD4; CD132; SCIDX; IL-2RG; SCIDX1; cytokine receptor common subunit gamma; CD132 antigen; IL-2 receptor subunit gamma; IL-2R subunit gamma; common cytokine receptor gamma chain; gammaC; interleukin 2 receptor, gamma; nonfunctional common cytokine receptor gamma chain
• Gene ID: 3561
• mRNA Refseq: NM_000206
• Protein Refseq: NP_000197
• MIM: 308380
• UniProt ID: P31785

Reviews

10/13/2022

Solubility is very good and can be easily dissolved in various buffers.

05/13/2022

Quality I use is very good and I have recommended this product to my colleagues and friends.

05/16/2021

The anti-pollution ability is very strong, not easy to be polluted.

Q&As

Are there any side effects of using this protein?

The use of IL2RG may cause chest tightness, skin itching, allergies and other side effects, you need to contact the doctor for timely treatment.

What is the dosage and use method of IL2RG?

The dosage and use method of IL2RG need to be determined according to the condition and individual situation, and need to be prescribed by a clinician.

Does IL2RG have a role and what is the mechanism?

Enhances the immunity of the human immune system by increasing the number and improving the function of immune cells in the body.

Which diseases is IL2RG used to treat?

IL2RG is mainly used in the treatment of immune deficiency diseases, such as systemic eosinophilic granulomatosis, X-linked immunodeficiency disease, etc.

What measures can be taken to mitigate the possible risks of IL2RG?

In view of possible risks, the use of IL2RG should be strictly in accordance with the doctor's advice, and avoid changing the dosage and frequency of medication.

What are the pharmacological characteristics of IL2RG?

IL2RG pharmacological features are contained in vivo to enhance the immunity of the human immune system by increasing the number of immune cells and improving their function.