Ins1
-
Official Full Name
insulin 1 -
Synonyms
INS1;insulin 1;insulin-1
Recombinant Proteins
- Mouse
- Rat
- Schizosaccharomyces pombe
- E.coli
- Yeast
- Mammalian Cells
- HEK293
- GST
- Non
- His
- Myc
- SUMO
- Avi
- Fc
Involved Pathway
Ins1 involved in several pathways and played different roles in them. We selected most pathways Ins1 participated on our site, such as Ras signaling pathway,Rap signaling pathway,cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with Ins1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Maturity onset diabetes of the young | NKX6-1,PAX4,INS2,RFX6,ONECUT1,SLC2A2,PAX6,HNF1A,BHLHA15,INS |
| Regulation of autophagy | Ifna15,INSB,IFNA8,IFNA6,ATG16L1,IFNA17,IFNA14,ATG14,GABARAPA,IFNA7 |
| HIF- signaling pathway | TCEB2,PRKCG,NOS2,MAP2K1,AKT1,HK2,PLCG2,PIK3R3,IFNGR2,PIK3CA |
| FoxO signaling pathway | TGFB1,CCNB3,CDKN2D,FOXO6,RAF1B,KRAS,TGFBR1A,STK11,PIK3R5,SMAD4 |
| Type II diabetes mellitus | IRS4,SOCS1,SOCS4,HKDC1,PKM2,SLC2A4,SOCS2,ADIPOQ,HK1,PIK3R1 |
| Prostate Cancer | NOXA1,PIK3CB,MAPK3,MAP4K1,NRAS,INS2,NFKB1,PDGFRB,INS,PDGFD |
| Insulin secretion | PDX1,KCNMB4,GNA11,ATP1B1,CCKAR,GCG,ATP1B2,KCNMB1,ADCYAP1,PLCB2 |
| Non-alcoholic fatty liver disease (NAFLD) | NDUFB5,NDUFA13,PRKAG2,Fasl,RXRA,SDHA,COX7A1,PKLR,PIK3CD,NDUFS3 |
| Rap signaling pathway | PRKCB,PGF,MAPK11,GRIN1,HGF,MAGI1,PRKCZ,PIK3R1,LPAR2,ITGB3 |
Protein Function
Ins1 has several biochemical functions, for example, chaperone binding,hormone activity,insulin receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Ins1 itself. We selected most functions Ins1 had, and list some proteins which have the same functions with Ins1. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| insulin receptor binding | INSL3,PHIP,DOK5,IRS2,SLC2A2,SNX1,IGF1,DOK3,IGF1R,DOK1 |
| chaperone binding | DNAJA3A,SOD1,C1orf182,DLST,HSP104,DNAJC3,SYVN1,CDKN1B,DNAJA2,GET4 |
| protease binding | TP53,F3,ITGAV,SERPINA1D,LCN2,SERPINA1A,ANXA2,DPP4,SERPINA1E,INSL3 |
| hormone activity | AMH,SST2,MLN,IGF1,PRL6A1,AVP,PTHLHA,CCL25,GH1,SMTLA |
Interacting Protein
Ins1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Ins1 here. Most of them are supplied by our site. Hope this information will be useful for your research of Ins1.
Gopc;Copb1
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