Recombinant Human IRF5 protein, Myc/DDK-tagged

• Cat.No.: IRF5-299H
• Product Overview: Recombinant Human IRF5 protein (transcript variant 1), fused to Myc/DDK-tag at C-terminus, was expressed in HEK293T cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
• Molecular Mass: 56.5 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining.
• Concentration: >50 μg/mL as determined by microplate BCA method.

Gene Information

• Gene Name: IRF5
• Official Symbol: IRF5
• Synonyms: interferon regulatory factor 5; SLEB10
• Gene ID: 3663
• mRNA Refseq: NM_001098629.3
• Protein Refseq: NP_001092099.1
• MIM: 607218
• UniProt ID: Q13568