Recombinant Human IRF5 Protein, His-tagged

• Cat.No.: IRF5-008H
• Product Overview: Recombinant human IRF5 protein((176-240, His-tag)), fused to His-tag at N-terminus, was expressed in E.coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 176-240 a.a.
• Description: This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Alternative promoter use and alternative splicing result in multiple transcript variants, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment.
• Molecular Mass: 10.7 kDa
• Purity: > 85 % by SDS - PAGE
• Concentration: 0.25 mg/ml (determined by Bradford assay)
• Storage Buffer: 20 mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 30% glycerol, 1mM DTT

Gene Information

• Gene Name: IRF5 interferon regulatory factor 5 [ Homo sapiens (human) ]
• Official Symbol: IRF5
• Synonyms: IRF5; interferon regulatory factor 5; SLEB10; interferon regulatory factor 5
• Gene ID: 3663
• mRNA Refseq: NM_001098627
• Protein Refseq: NP_001092097
• MIM: 607218
• UniProt ID: Q13568