KLRB1

  • Official Full Name

    killer cell lectin-like receptor subfamily B, member 1

  • Overview

    Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]
  • Synonyms

    KLRB1; killer cell lectin-like receptor subfamily B, member 1; NKR; CD161; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A; killer cell lectin-like receptor subfamily B member 1; C-type lectin domain family 5 member B; natural killer cell surface protein P1A;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus
  • Human
  • Mouse
  • Rat
  • Rhesus monkey
  • E.coli
  • HEK293
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • Fc
  • His
  • GST
  • His (Fc)
  • Avi
  • His|HIgG
  • His|T7
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human KLRB1-5701H Recombinant Human KLRB1 protein, His & T7-tagged E.coli His/T7 Lys73~Ser188 (Accession # Q12918)
Human KLRB1-4896HCL Recombinant Human KLRB1 293 Cell Lysate HEK293 N/A
Human KLRB1-3698H Recombinant Human KLRB1 protein, His-tagged E.coli His 68-225 aa
Human KLRB1-4919H Recombinant Human KLRB1 protein, His-tagged HEK293 His Gln 67 - Ser 225
Human KLRB1-228H Recombinant Human KLRB1 Protein, hIgG-His-tagged Insect Cell His/HIgG 67-225aa
Human KLRB1-30H Recombinant Human KLRB1 protein, Fc-tagged HEK293 Fc Gln67-Ser225
Human KLRB1-087H Recombinant Human KLRB1 Protein, C-His-tagged E.coli C-His
Human KLRB1-32H Recombinant Human KLRB1 protein, His-tagged HEK293 His Gln67-Ser225
Human KLRB1-4918H Recombinant Human KLRB1 Protein, GST-tagged Wheat Germ GST
Human KLRB1-31H Recombinant Human KLRB1 protein, Fc-tagged HEK293 Fc Lys68-Ser225
Human KLRB1-4359H Recombinant Human KLRB1 Protein (Lys68-Ser225), N-Fc tagged Mammalian cells N-Fc Lys68-Ser225
Human KLRB1-4356H Recombinant Human KLRB1 Protein (Lys68-Ser225), C-His tagged Mammalian cells C-His Lys68-Ser225
Human KLRB1-33HB Recombinant Human KLRB1 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Gln67-Ser225
Human KLRB1-1034H Recombinant Human KLRB1 Protein (Lys73-Ser188), N-His tagged E.coli N-His Lys73-Ser188
Human KLRB1-4357H Recombinant Human KLRB1 Protein (Gln67-Ser225), C-Fc tagged Mammalian cells C-Fc Gln67-Ser225
Mouse KLRB1-8777M Recombinant Mouse KLRB1 Protein Mammalian Cell His
Mouse KLRB1-4886M Recombinant Mouse KLRB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse KLRB1-4886M-B Recombinant Mouse KLRB1 Protein Pre-coupled Magnetic Beads HEK293
Rat KLRB1-3295R Recombinant Rat KLRB1 Protein Mammalian Cell His
Rat KLRB1-2951R Recombinant Rat KLRB1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Klrb1-1072R Recombinant Rat Klrb1 Protein, His-tagged E.coli N-His Gln64-Val214
Rat KLRB1-2951R-B Recombinant Rat KLRB1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus monkey KLRB1-1588R Recombinant Rhesus Monkey KLRB1 Protein HEK293 N/A
Cynomolgus KLRB1-160CB Recombinant Cynomolgus KLRB1 protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Gln67-Leu227
Cynomolgus KLRB1-160C Recombinant Cynomolgus KLRB1 protein, His-Avi-tagged HEK293 His-Avi Gln67-Leu227
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

KLRB1 involved in several pathways and played different roles in them. We selected most pathways KLRB1 participated on our site, such as Malaria, which may be useful for your reference. Also, other proteins which involved in the same pathway with KLRB1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
MalariaICAM1;TGFB1;HBA-A2;THBS1;GYPA;SELE;IL6;ITGB2;SDC2

KLRB1 has several biochemical functions, for example, carbohydrate binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by KLRB1 itself. We selected most functions KLRB1 had, and list some proteins which have the same functions with KLRB1. You can find most of the proteins on our site.

Function Related Protein
carbohydrate bindingLMAN1L;LAYN;GALNT3;SIGLEC5;CD248;APCS;BCAN;SBP;CLEC7A
transmembrane signaling receptor activityEBP;GPR124;TNFRSF10C;BAI2;GPR182;OR4C13;CD5;GHRHRA;BCAM

KLRB1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with KLRB1 here. Most of them are supplied by our site. Hope this information will be useful for your research of KLRB1.

rpoB

Research Area

Related articles

Hoffmann, J; Shmeleva, EV; et al. Myocardial Ischemia and Reperfusion Leads to Transient CD8 Immune Deficiency and Accelerated Immunosenescence in CMV-Seropositive Patients. CIRCULATION RESEARCH 116:87-U222(2015).
Shimizu, K; Sato, Y; et al. KLRG(+) invariant natural killer T cells are long-lived effectors. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 111:12474-12479(2014).
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