LAMP2
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Official Full Name
lysosomal-associated membrane protein 2 -
Overview
The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008] -
Synonyms
LAMP2;lysosomal-associated membrane protein 2;LAMPB;CD107b;LAMP-2;LGP110;lysosome-associated membrane glycoprotein 2;CD107 antigen-like family member B
Recombinant Proteins
- Human
- Cynomolgus
- Chicken
- Zebrafish
- Rhesus macaque
- Mouse
- Rat
- Mus musculus
- Cricetulus griseus
- E.coli
- Human Cells
- Mammalian Cells
- Wheat Germ
- HEK293
- Insect Cells
- His
- GST
- Non
- Avi
- Fc
- DDK
- Myc
- Flag
Involved Pathway
LAMP2 involved in several pathways and played different roles in them. We selected most pathways LAMP2 participated on our site, such as Lysosome,Phagosome,Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with LAMP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Tuberculosis | FCER1G,Casp3,CAMK2G,CEBPG,ITGAM,MAPK9,IFNA8,HLA-DRB3,PPP3CB,IFNA7 |
| Lysosome | SGSH,GALC,DNASE2B,CTSC,CTSBA,MFSD8,AP1S3B,AP1M3,HEXA,CTSG |
| Phagosome | MSR1,RAB5B,DYNC2H1,BLB2,SEC61A1,NCF2,RAC1,THBS3,HLA-C,SEC22BB |
Protein Function
LAMP2 has several biochemical functions, for example, enzyme binding,protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LAMP2 itself. We selected most functions LAMP2 had, and list some proteins which have the same functions with LAMP2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| enzyme binding | GOT2,ABCD1,PTPLAD2,HLCS,ZFP36,PIAS3,N4BP2L2,RPS19BP1,HMGA1,RPS3 |
| protein binding | PRKCI,IRF5,FBXO9,DGAT1,CCDC87,ASS1,UXT,MCM5,REEP1,CCND3 |
Interacting Protein
LAMP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LAMP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LAMP2.
LRRK2;RRAGB;RPTOR;PIAS4;b3xyc5_sollc;pi3p;cona_canen;ATP6V1A;Map1lc3b;SOD1;ADRB2;HSPA8;CLCN7;Sppl2a
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References
- Kondo, T; Namiki, T; et al. Oculocutaneous albinism: Developing novel antibodies targeting the proteins associated with OCA2 and OCA4. JOURNAL OF DERMATOLOGICAL SCIENCE 77:21-27(2015).
- Berguig, GY; Convertine, AJ; et al. Intracellular Delivery and Trafficking Dynamics of a Lymphoma-Targeting Antibody-Polymer Conjugate. MOLECULAR PHARMACEUTICS 9:3506-3514(2012).
