LAMP2

  • Official Full Name

    lysosomal-associated membrane protein 2

  • Overview

    The protein encoded by this gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may play a role in tumor cell metastasis. It may also function in the protection, maintenance, and adhesion of the lysosome. Alternative splicing of this gene results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2008]
  • Synonyms

    LAMP2; lysosomal-associated membrane protein 2; LAMPB; CD107b; LAMP-2; LGP110; lysosome-associated membrane glycoprotein 2; CD107 antigen-like family member B;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Chicken
  • Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
  • Cynomolgus Monkey
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human Cell
  • Insect Cell
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • MYC
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human LAMP2-27946TH Recombinant Human LAMP2 Wheat Germ N/A 98 amino acids
Human LAMP2-554H Recombinant Human LAMP2 Protein, His-tagged HEK293 His
Human LAMP2-729H Recombinant Human LAMP2 Protein HEK293 N/A
Human LAMP2-6992H Recombinant Human LAMP2 protein, His & GST-tagged E.coli His/GST Lys193~Asn375 (Accession # P13473)
Human LAMP2-163H Recombinant Human LAMP2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human LAMP2-4417H Recombinant Human LAMP2 Protein (Met1-Phe375), C-His tagged Mammalian cells C-His Met1-Phe375
Human LAMP2-3391H Recombinant Human LAMP2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human LAMP2-233H Recombinant Human LAMP2 Protein, His-tagged Insect Cell His 29-375aa
Human LAMP2-5886H Recombinant Human LAMP2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human LAMP2-2647H Recombinant Human LAMP2 protein(131-230 aa), C-His-tagged E.coli C-His 131-230 aa
Human LAMP2-6251H Recombinant Human LAMP2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human LAMP2-3727H Recombinant Human LAMP2 protein, GST-tagged E.coli GST 29-230 aa
Human LAMP2-2871H Recombinant Human LAMP2 protein, His-tagged E.coli His 29 - 230 aa
Human LAMP2-1277H Recombinant Human LAMP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human LAMP2-170HFL Recombinant Full Length Human LAMP2 Protein, C-Flag-tagged Mammalian cells Flag
Human LAMP2-1241H Recombinant Human LAMP2 Protein (Leu29-Gln366), N-His tagged E.coli N-His Leu29-Gln366
Human LAMP2-1277H-B Recombinant Human LAMP2 Protein Pre-coupled Magnetic Beads HEK293
Human LAMP2-4418H Recombinant Human LAMP2 Protein (Leu29-Ile375), C-His tagged Mammalian cells C-His Leu29-Ile375
Mouse Lamp2-6993M Recombinant Mouse Lamp2 protein, His & GST-tagged E.coli His/GST Asn295~Thr410 (Accession # P17047)
Mouse Lamp2-6974M Recombinant Mouse Lamp2 protein(Leu26-Asn379), His-tagged HEK293 C-His Leu26-Asn379
Mouse LAMP2-1756MCL Recombinant Mouse LAMP2 cell lysate Human Cell N/A
Mouse Lamp2-1292M Recombinant Mouse Lamp2 Protein, MYC/DDK-tagged HEK293T MYC/DDK
Rat Lamp2-6994R Recombinant Rat Lamp2 protein, His-tagged E.coli His Ala191~Glu362 (Accession # P17046)
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) RFL34345CF Recombinant Full Length Cricetulus Griseus Lysosome-Associated Membrane Glycoprotein 2(Lamp2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (29-410)
Cynomolgus Monkey LAMP2-106C Recombinant Cynomolgus LAMP2, His tagged Human Cell His
Cynomolgus Monkey LAMP2-987CCL Recombinant Cynomolgus LAMP2 cell lysate Human Cell N/A
Homo sapiens (Human) RFL7518HF Recombinant Full Length Human Lysosome-Associated Membrane Glycoprotein 2(Lamp2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (29-410)
Mus musculus (Mouse) RFL27349MF Recombinant Full Length Mouse Lysosome-Associated Membrane Glycoprotein 2(Lamp2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (26-415)
Rattus norvegicus (Rat) RFL4114RF Recombinant Full Length Rat Lysosome-Associated Membrane Glycoprotein 2(Lamp2) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (26-411)
Rhesus Macaque LAMP2-2457R Recombinant Rhesus monkey LAMP2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque LAMP2-2278R Recombinant Rhesus Macaque LAMP2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque LAMP2-2278R-B Recombinant Rhesus Macaque LAMP2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish LAMP2-2200Z Recombinant Zebrafish LAMP2 Mammalian Cell His
Chicken LAMP2-1145C Recombinant Chicken LAMP2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • Other Resource

LAMP2 involved in several pathways and played different roles in them. We selected most pathways LAMP2 participated on our site, such as Lysosome, Phagosome, Tuberculosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with LAMP2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
LysosomeAP3B2;TCIRG1;NAGA;ATP6AP1;ATP6V0A1B;LGMN;MCOLN1;CTSSB.1;TPP1
PhagosomeDYNC1I1;TUBA1C;HLA-DOA;ATP6V1F;ATP6V1C1;ATP6V0A1;ATP6V1G2;ATP6AP1B;CTSL1B
TuberculosisIRAK1;IL6;H2-AA;CD209;LSP1;CASP9;FCGR1A;EEA1;TLR9

LAMP2 has several biochemical functions, for example, enzyme binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by LAMP2 itself. We selected most functions LAMP2 had, and list some proteins which have the same functions with LAMP2. You can find most of the proteins on our site.

Function Related Protein
enzyme bindingTBP;DNMT3L;HIST1H2AI;PLSCR1;HMGA1-RS1;RPS2;GNB2L1;MAPK14;CYP2C8
protein bindingCDA;AMY1A;MRE11A;SETBP1;ULK3;RIT1;RBM39;SOX7;FAM189B

LAMP2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LAMP2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LAMP2.

LRRK2; RRAGB; RPTOR; PIAS4; b3xyc5_sollc; pi3p; cona_canen; ATP6V1A; Map1lc3b; SOD1; ADRB2; HSPA8; CLCN7; Sppl2a

Research Area

Related articles

Kondo, T; Namiki, T; et al. Oculocutaneous albinism: Developing novel antibodies targeting the proteins associated with OCA2 and OCA4. JOURNAL OF DERMATOLOGICAL SCIENCE 77:21-27(2015).
Berguig, GY; Convertine, AJ; et al. Intracellular Delivery and Trafficking Dynamics of a Lymphoma-Targeting Antibody-Polymer Conjugate. MOLECULAR PHARMACEUTICS 9:3506-3514(2012).
  • Q&As
  • Reviews

Q&As (5)

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How does LAMP2 protein function in the context of cardiovascular diseases? 06/10/2022

LAMP2 may play a role in maintaining cardiac function and the clearance of damaged organelles in the heart, making it relevant to cardiovascular diseases.

How are mutations in the LAMP2 gene detected in clinical practice? 05/01/2022

Mutations in the LAMP2 gene can be identified through genetic testing, such as DNA sequencing.

What are the potential therapeutic implications of targeting LAMP2 in Danon disease? 04/25/2022

Targeting LAMP2 function or expression may represent a potential therapeutic strategy for treating Danon disease and other lysosomal storage disorders.

What are the clinical implications of LAMP2 deficiency? 02/08/2018

LAMP2 deficiency has been associated with Danon disease, a rare genetic disorder characterized by cardiomyopathy, skeletal myopathy, and intellectual disability.

How is LAMP2 protein involved in lysosomal function? 05/25/2017

LAMP2 is involved in maintaining the integrity and stability of lysosomal membranes, as well as facilitating the fusion of lysosomes with autophagosomes during autophagy.

Customer Reviews (3)

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Reviews
12/20/2021

    LAMP2 is extensively used in protein electron microscopy structure analysis due to its compatibility with this technique, providing crucial insights into molecular architectures.

    12/11/2017

      One aspect that sets the LAMP2 Protein apart is the excellent technical support provided by the manufacturer.

      08/07/2016

        I have found the LAMP2 Protein to be highly stable, enabling long-term experiments without compromising its performance.

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