|Official Full Name||lipase A, lysosomal acid, cholesterol esterase|
|Background||This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]|
|Synonyms||LIPA; lipase A, lysosomal acid, cholesterol esterase; LAL; CESD; lysosomal acid lipase/cholesteryl ester hydrolase; sterol esterase; cholesteryl esterase; lysosomal acid lipase; cholesterol ester hydrolase; acid cholesteryl ester hydrolase;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
lipa involved in several pathways and played different roles in them. We selected most pathways lipa participated on our site, such as Steroid biosynthesis, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with lipa were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Steroid biosynthesis||SQLE; LSS; SOAT1; DHCR7; LIPA; CYP51; MSMO1; CYP2R1; DHCR24; SC4MOL|
|Lysosome||IDUA; CTSL1B; GGA1; CTNS; NAGA; Ctsl; SORT1; ARSB; ATP6V0CA; CTSSB.2|
lipa has several biochemical functions, for example, lipase activity, sterol esterase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by lipa itself. We selected most functions lipa had, and list some proteins which have the same functions with lipa. You can find most of the proteins on our site.
|lipase activity||LYPLA1; GOLT1BB; C2orf43; CELL; Aadacl3; NOTUM1A; GOLT1B; CEL.1; AADAC; PNPLA7|
|sterol esterase activity||Cel; CES1D; CES3; CEL.1; CES5A; CES1; LIPA|
lipa has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with lipa here. Most of them are supplied by our site. Hope this information will be useful for your research of lipa.