lipa

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lipa

Official Full Name lipase A, lysosomal acid, cholesterol esterase
Background This gene encodes lipase A, the lysosomal acid lipase (also known as cholesterol ester hydrolase). This enzyme functions in the lysosome to catalyze the hydrolysis of cholesteryl esters and triglycerides. Mutations in this gene can result in Wolman disease and cholesteryl ester storage disease. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2014]
Synonyms LIPA; lipase A, lysosomal acid, cholesterol esterase; LAL; CESD; lysosomal acid lipase/cholesteryl ester hydrolase; sterol esterase; cholesteryl esterase; lysosomal acid lipase; cholesterol ester hydrolase; acid cholesteryl ester hydrolase;
    • Species :
    • Bacillus subtilis
    • Bartonella Henselae
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E. coli or Yeast
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Yeast
    • Tag :
    • GST
    • His
    • T7
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human LIPA-11H Recombinant Human LIPA, MYC/DDK-tagged HEK293 Myc/DDK
    Human LIPA-2158H Recombinant Human LIPA Protein (22-399 aa), His-tagged Yeast His
    Human LIPA-4727HCL Recombinant Human LIPA 293 Cell Lysate HEK293 N/A
    Human LIPA-627H Recombinant Human LIPA Protein (22-399 aa), GST-tagged E.coli GST
    Human LIPA-6304H Recombinant Human LIPA Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Lipa-1321M Recombinant Mouse Lipa Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Lipa-7937M Recombinant Mouse Lipa protein, His & T7-tagged E.coli His/T7
    Rat Lipa-7938R Recombinant Rat Lipa protein, His & T7-tagged E.coli His/T7
    Rhesus Macaque LIPA-2523R Recombinant Rhesus monkey LIPA Protein, His-tagged Mammalian Cell His
    Bartonella Henselae LIPA-2402B Recombinant Bartonella Henselae LIPA Protein (1-320 aa), His-tagged Yeast His
    Bacillus subtilis LIPA-2533B Recombinant Bacillus subtilis LIPA protein, His-tagged E. coli or Yeast His

    lipa involved in several pathways and played different roles in them. We selected most pathways lipa participated on our site, such as Steroid biosynthesis, Lysosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with lipa were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Steroid biosynthesis SQLE; LSS; SOAT1; DHCR7; LIPA; CYP51; MSMO1; CYP2R1; DHCR24; SC4MOL
    Lysosome IDUA; CTSL1B; GGA1; CTNS; NAGA; Ctsl; SORT1; ARSB; ATP6V0CA; CTSSB.2

    lipa has several biochemical functions, for example, lipase activity, sterol esterase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by lipa itself. We selected most functions lipa had, and list some proteins which have the same functions with lipa. You can find most of the proteins on our site.

    Function Related Protein
    lipase activity LYPLA1; GOLT1BB; C2orf43; CELL; Aadacl3; NOTUM1A; GOLT1B; CEL.1; AADAC; PNPLA7
    sterol esterase activity Cel; CES1D; CES3; CEL.1; CES5A; CES1; LIPA

    lipa has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with lipa here. Most of them are supplied by our site. Hope this information will be useful for your research of lipa.

    Frohnecke, N; Klein, S; et al. Protein-protein interaction studies provide evidence for electron transfer from ferredoxin to lipoic acid synthase in Toxoplasma gondii. FEBS LETTERS 589:31-36(2015).
    Zhao, FH; Zhu, FC; et al. Baseline prevalence and type distribution of human papillomavirus in healthy Chinese women aged 18-25 years enrolled in a clinical trial. INTERNATIONAL JOURNAL OF CANCER 135:2604-2611(2014).

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