Recombinant Bartonella Henselae LIPA Protein (1-320 aa), His-tagged

• Cat.No.: LIPA-2402B
• Product Overview: Recombinant Bartonella Henselae (strain ATCC 49882/DSM 28221/Houston 1) (Rochalimaea henselae) LIPA Protein (1-320 aa) is produced by Yeast expression system. This protein is fused with a 10xHis tag at the N-terminal. Protein Description: Full Length.

Specification

• Description: Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
• Source: Yeast
• Species: Bartonella Henselae
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 38.7 kDa
• Protein length: 1-320 aa
• AA Sequence: MVTVVDRVTDRRLRHPEKAHRPDTS VQKKPDWIRVKAPTSQVYKETHGIV RAHKLVTVCEEAGCPNIGECWSQRH ASFMILGEICTRACAFCNVATGIPF AVDENEPERVADAVARMELKHVVIT SVDRDDLADGGAEHFAKVIYAIRRK APKTTIEVLTPDFRHKDGALEIVVA AKPDVFNHNLETVPSKYLKVRPGAR YFHSIRLLQRVKELDPTIFTKSGIM VGLGEERNEILQLMDDLRSADVDFM TIGQYLQPTRKHHPVIRFVPPEEFE SFAKIGKVKGFLHMASNPLTRSSHH AGDDFAILQKARDEKFALQR
• Purity: > 85% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.
• Synonyms: lipA
• UniProt ID: Q6G401

Gene Information

• Synonyms: lipA
• UniProt ID: Q6G401

Reviews

03/02/2019

Its reliable and accurate performance ensures dependable results, contributing to the advancement of scientific knowledge in various fields of study.

01/18/2018

The reliable performance of the LIPA protein in ELISA and its compatibility with protein electron microscopy structure analysis make it an excellent choice for a wide range of research studies.

03/05/2017

Their knowledgeable and responsive team assists in troubleshooting and finding solutions to any experimental challenges that may arise.

Q&As

How does LIPA protein deficiency affect lipid metabolism?

LIPA protein deficiency impairs the breakdown of cholesterol esters and triglycerides, leading to their accumulation in various tissues and organs.

How is LIPA protein deficiency diagnosed?

Diagnosis of LIPA protein deficiency is typically made through genetic testing and measurement of LIPA enzyme activity in blood samples.

Are there any specific dietary recommendations for individuals with LIPA protein deficiency?

Patients with LIPA protein deficiency are often advised to follow a low-fat, high-carbohydrate diet to help manage their lipid levels.

How does LIPA protein deficiency affect the liver?

LIPA protein deficiency can result in the accumulation of cholesterol esters and triglycerides in the liver, leading to liver damage and dysfunction.

Are there any ongoing research efforts focused on LIPA protein and its clinical applications?

Yes, researchers are actively studying LIPA protein deficiency and potential therapeutic approaches, including gene therapy and novel enzyme replacement strategies.