Recombinant Human LIPA protein(22-399aa), His-tagged
Cat.No. : | LIPA-532H |
Product Overview : | Recombinant Human LIPA protein(P38571)(22-399aa), fused with N-terminal His tag, was expressed in E.coli. |
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Source : | E.coli |
Species : | Human |
Tag : | N-His |
Protein length : | 22-399aa |
Form : | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Molecular Mass : | 47.1 kDa |
AASequence : | SGGKLTAVDPETNMNVSEIISYWGF PSEEYLVETEDGYILCLNRIPHGRK NHSDKGPKPVVFLQHGLLADSSNWV TNLANSSLGFILADAGFDVWMGNSR GNTWSRKHKTLSVSQDEFWAFSYDE MAKYDLPASINFILNKTGQEQVYYV GHSQGTTIGFIAFSQIPELAKRIKM FFALGPVASVAFCTSPMAKLGRLPD HLIKDLFGDKEFLPQSAFLKWLGTH VCTHVILKELCGNLCFLLCGFNERN LNMSRVDVYTTHSPAGTSVQNMLHW SQAVKFQKFQAFDWGSSAKNYFHYN QSYPPTYNVKDMLVPTAVWSGGHDW LADVYDVNILLTQITNLVFHESIPE WEHLDFIWGLDAPWRLYNKIINLMR KYQ |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Storage : | Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. |
Gene Name : | LIPA lipase A, lysosomal acid, cholesterol esterase [ Homo sapiens ] |
Official Symbol : | LIPA |
Synonyms : | LIPA; lipase A, lysosomal acid, cholesterol esterase; lysosomal acid lipase/cholesteryl ester hydrolase; CESD; LAL; Wolman disease; sterol esterase; cholesteryl esterase; lysosomal acid lipase; cholesterol ester hydrolase; acid cholesteryl ester hydrolase; |
Gene ID : | 3988 |
mRNA Refseq : | NM_000235 |
Protein Refseq : | NP_000226 |
MIM : | 613497 |
UniProt ID : | P38571 |
Products Types
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LIPA-627H | Recombinant Human LIPA Protein (22-399 aa), GST-tagged | +Inquiry |
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LIPA-2158H | Recombinant Human LIPA Protein (22-399 aa), His-tagged | +Inquiry |
◆ Lysates | ||
LIPA-4727HCL | Recombinant Human LIPA 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionLIPA protein deficiency impairs the breakdown of cholesterol esters and triglycerides, leading to their accumulation in various tissues and organs.
Diagnosis of LIPA protein deficiency is typically made through genetic testing and measurement of LIPA enzyme activity in blood samples.
Patients with LIPA protein deficiency are often advised to follow a low-fat, high-carbohydrate diet to help manage their lipid levels.
LIPA protein deficiency can result in the accumulation of cholesterol esters and triglycerides in the liver, leading to liver damage and dysfunction.
Yes, researchers are actively studying LIPA protein deficiency and potential therapeutic approaches, including gene therapy and novel enzyme replacement strategies.
Customer Reviews (3)
Write a reviewIts reliable and accurate performance ensures dependable results, contributing to the advancement of scientific knowledge in various fields of study.
The reliable performance of the LIPA protein in ELISA and its compatibility with protein electron microscopy structure analysis make it an excellent choice for a wide range of research studies.
Their knowledgeable and responsive team assists in troubleshooting and finding solutions to any experimental challenges that may arise.
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