NRTN

  • Official Full Name

    neurturin

  • Overview

    Neurturin is a member of the TGF-beta subfamily, TRN. This gene signals through RET and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. [provided by RefSeq, Jul 2008]

  • Synonyms

    NRTN;neurturin;NTN;prepro-neurturin

Recombinant Proteins

  • Human
  • Mouse
  • Chicken
  • E.coli
  • Mammalian Cells
  • HEK293
  • Non
  • His
  • Avi
  • Fc

    Involved Pathway

    NRTN involved in several pathways and played different roles in them. We selected most pathways NRTN participated on our site, such as Axon guidance,Developmental Biology,NCAM signaling for neurite out-growth, which may be useful for your reference. Also, other proteins which involved in the same pathway with NRTN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Axon guidance RHOB,COL6A2,SEMA3A,DPYSL4,EFNA3,NTNG1,COL6A3,RGMB,CNKSR1,DUSP4
    Developmental Biology FRS2B,PEA15,SEMA3AA,FGFR1B,CAP1,ACTR2B,MEF2AA,SCN8A,MYL12A,MED20
    NCAM signaling for neurite out-growth COL9A1A,ST8SIA2,GDNF,GFRA1,PSPN,GFRA4,GFRA2,COL9A1B
    NCAM1 interactions GDNF,GFRA4,PSPN,GFRA2,COL9A1B,GFRA1,COL9A1A

    Protein Function

    NRTN has several biochemical functions, for example, growth factor activity,receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NRTN itself. We selected most functions NRTN had, and list some proteins which have the same functions with NRTN. You can find most of the proteins on our site.

    Function Related Protein
    receptor binding STOML2,HCST,PTK2B,NPPC,PKD2,ADM,Itga10&Itgb1,CROT,PPP2R4,MBL2
    growth factor activity VHL,GDF5,NGF,FGF14,BMP7A,JAG1,IL8L2,Il2,FGF18B,GDF11

    Interacting Protein

    NRTN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NRTN here. Most of them are supplied by our site. Hope this information will be useful for your research of NRTN.

    Resources

    Gene Families

    Research Area

    References

    Reviews

    Write a review

    Q&As

    Ask a question

    Ask a Question for All NRTN Products

    Required fields are marked with *

    My Review for All NRTN Products

    Required fields are marked with *