Active Recombinant Human NRTN Protein (Ala96-Val197), C-His tagged, Animal-free, Carrier-free
Cat.No. : | NRTN-236H |
Product Overview : | Recombinant Human NRTN Protein (Ala96-Val197) with C-His tag was expressed in E. coli and Animal-free as well as Carrier-free. |
- Specification
- Gene Information
- Related Products
Description : | Human Neurturin is a 22 kDa cytokine with 197 amino acid residues. Neurturin belongs to the same TGF-beta (transforming Growth Factors β) family. When Neurturin binds to GFRα-2 (GPI-linked receptor termed GDNF family receptor α-2), this complex activates Ret receptor tyrosine kinase and its downstream signaling pathway. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Form : | Lyophilized |
Bio-activity : | Measure by its ability to induce proliferation in SH-SY5Y cells. The ED50 for this effect is < 50 ng/mL. |
Molecular Mass : | The protein has a calculated MW of 12.62 kDa. The protein migrates as 13 kDa under reducing condition (SDS-PAGE analysis). |
Protein Length : | Ala96-Val197 |
Endotoxin : | < 0.1 EU/μg of the protein by the LAL method. |
Purity : | >98% as determined by SDS-PAGE analysis. |
Storage : | This product is stable after storage at: -20 centigrade for 12 months in lyophilized state from date of receipt. -20 or -80 centigrade for 1 month under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. |
Storage Buffer : | Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. |
Reconstitution : | It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 200 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved. |
Shipping : | The product is shipped with polar packs. Upon receipt, store it immediately at -20 centigrade or lower for long term storage. |
Gene Name : | NRTN neurturin [ Homo sapiens (human) ] |
Official Symbol : | NRTN |
Synonyms : | NRTN; neurturin; NTN; |
Gene ID : | 4902 |
mRNA Refseq : | NM_004558 |
Protein Refseq : | NP_004549 |
MIM : | 602018 |
UniProt ID : | Q99748 |
Products Types
◆ Recombinant Protein | ||
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NRTN-259H | Recombinant Active Human NRTN Protein, His-tagged(C-ter) | +Inquiry |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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