| Species : |
Human |
| Source : |
E.coli |
| Tag : |
Non |
| Description : |
Human Neurturin (NTN) and human GDNF comprise a family of TGF-beta related neurotrophic factor which have trophic influences on a variety of neuronal populations. Neurturin promotes the survivability of certain sympathetic and sensory neurons through interaction with distinct set of GDNF-like receptors. |
| Purity : |
98 % (SDS-PAGE, HPLC). |
| Endotoxin Level : |
< 0.1 ng per ug of Neurturin. |
| Stabilizer : |
None. |
| Formulation : |
Lyophilized. |
| Biological Activity : |
Human Neurturin is fully biologically active when compared to standards. Human Neurturin at a concentration of 50-100 ng/ml will support the survival of 65% of newborn rat sympathetic neurons. |
| Reconstitution : |
The lyophilized human Neurturin can be reconstituted in water to a concentration of 1 mg/ml. This solution can be diluted into other buffered solutions or stored at -20°C for future use. For most in vitro applications, Neurturin exerts its biological activity in the concentration of 0.1 to 10 ng/ml. |
| Stability : |
The lyophilized protein, though stable at room temperature, is best stored desiccated below 0°C. Reconstituted Neurturin should be stored in working aliquots at -20°C. Avoid repeated freeze-thaw cycles. |
| Pathways : |
Axon guidance |
