Active Recombinant Human NRTN Protein
| Cat.No. : | NRTN-090H |
| Product Overview : | The mature recombinant human Neurturin protein consists of 102 amino acids (96-197) without tag was expressed in E. coli. |
- Specification
- Gene Information
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| Description : | This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease. |
| Source : | E. coli |
| Species : | Human |
| Bio-activity : | Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED50 for this effect is typically 20-80 ng/mL. |
| Molecular Mass : | 23.6 kDa |
| Product-Related Proteins : | 96-197 |
| Endotoxin : | < 0.1 EU/μg of the protein as determined by the LAL method |
| Purity : | > 95 % as determined by SDS-PAGE |
| Storage : | At -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Storage Buffer : | PBS |
| Gene Name : | NRTN neurturin [ Homo sapiens (human) ] |
| Official Symbol : | NRTN |
| Synonyms : | NRTN; neurturin; NTN; neurturin; prepro-neurturin |
| Gene ID : | 4902 |
| mRNA Refseq : | NM_004558 |
| Protein Refseq : | NP_004549 |
| MIM : | 602018 |
| UniProt ID : | Q99748 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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