Recombinant Mouse Neurotrophic Tyrosine Kinase, Receptor, Type 3, His-tagged
Cat.No. : | Ntrk3-908M |
Product Overview : | A DNA sequence encoding the extracellular domain of mouse TrkC (NP_032772.3) (Met 1-Thr 429) was expressed, with a C-terminal polyhistidine tag. |
- Specification
- Gene Information
- Related Products
Cat. No. : | Ntrk3-908M |
Description : | Ntrk3 is a single-pass type I membrane protein. Ntrk3 belongs to the protein kinase superfamily and insulin receptor subfamily. Mouse Ntrk3 is a 825 amino acid (aa) protein and is widely expressed but mainly in nervous tissue. It contains two Ig-like C2-type (immunoglobulin-like) domains, one LRR (leucine-rich) repeats and one protein kinase domain. Ntrk3 is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. |
Source : | Mouse |
Host : | Human Cells |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Purity : | > 95 % as determined by SDS-PAGE |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70°C. |
Predicted N terminal : | Cys 32 |
Molecular Mass : | The secreted recombinant mouse TrkC comprises 409 amino acids and has a calculated molecular mass of 46.1 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 100-110 kDa band in SDS-PAGE under reducing conditions. |
Storage : | Store it under sterile conditions at -70°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles. |
Gene Name : | Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 [ Mus musculus ] |
Official Symbol : | Ntrk3 |
Synonyms : | Ntrk3; neurotrophic tyrosine kinase, receptor, type 3; TrkC; AW125844; NT-3 growth factor receptor; trk-C; GP145-TrkC; OTTMUSP00000023300; OTTMUSP00000023301; trkC tyrosine kinase |
Gene ID : | 18213 |
mRNA Refseq : | NM_008746 |
Protein Refseq : | NP_032772 |
UniProt ID : | Q6VNS1 |
Chromosome Location : | 7 |
Pathway : | Neurotrophin signaling pathway |
Function : | ATP binding; kinase activity; neurotrophin receptor activity; nucleotide binding; protein binding; protein kinase activity; protein tyrosine kinase activity; receptor activity; transferase activity; transferase activity, transferring phosphorus-containing groups; transmembrane receptor protein tyrosine kinase activity |
Products Types
◆ Recombinant Protein | ||
NTRK3-3765R | Recombinant Rat NTRK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ntrk3-009M | Recombinant Mouse Ntrk3 Protein, His-tagged | +Inquiry |
Ntrk3-035M | Recombinant Mouse Ntrk3 Protein, His-tagged | +Inquiry |
NTRK3-4468H | Recombinant Human NTRK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
NTRK3-2938R | Recombinant Rhesus Macaque NTRK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
NTRK3-2583MCL | Recombinant Mouse NTRK3 cell lysate | +Inquiry |
NTRK3-2825HCL | Recombinant Human NTRK3 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1632 | U2OS TrkC Bioassay Kit | +Inquiry |
Kit-1633 | TrkC Functional Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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