Recombinant Mouse Neurotrophic Tyrosine Kinase, Receptor, Type 3, His-tagged
Cat.No. : | Ntrk3-908M |
Product Overview : | A DNA sequence encoding the extracellular domain of mouse TrkC (NP_032772.3) (Met 1-Thr 429) was expressed, with a C-terminal polyhistidine tag. |
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Cat. No. : | Ntrk3-908M |
Description : | Ntrk3 is a single-pass type I membrane protein. Ntrk3 belongs to the protein kinase superfamily and insulin receptor subfamily. Mouse Ntrk3 is a 825 amino acid (aa) protein and is widely expressed but mainly in nervous tissue. It contains two Ig-like C2-type (immunoglobulin-like) domains, one LRR (leucine-rich) repeats and one protein kinase domain. Ntrk3 is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. |
Source : | Mouse |
Host : | Human Cells |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5%-8% trehalose and mannitol are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. |
Purity : | > 95 % as determined by SDS-PAGE |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70°C. |
Predicted N terminal : | Cys 32 |
Molecular Mass : | The secreted recombinant mouse TrkC comprises 409 amino acids and has a calculated molecular mass of 46.1 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 100-110 kDa band in SDS-PAGE under reducing conditions. |
Storage : | Store it under sterile conditions at -70°C upon receiving. Recommend to aliquot the protein into smaller quantities for optimal storage. Avoid repeated freeze-thaw cycles. |
Protein length : | Met1-Thr429 |
Gene Name : | Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 [ Mus musculus ] |
Official Symbol : | Ntrk3 |
Synonyms : | Ntrk3; neurotrophic tyrosine kinase, receptor, type 3; TrkC; AW125844; NT-3 growth factor receptor; trk-C; GP145-TrkC; OTTMUSP00000023300; OTTMUSP00000023301; trkC tyrosine kinase |
Gene ID : | 18213 |
mRNA Refseq : | NM_008746 |
Protein Refseq : | NP_032772 |
UniProt ID : | Q6VNS1 |
Chromosome Location : | 7 |
Pathway : | Neurotrophin signaling pathway |
Function : | ATP binding; kinase activity; neurotrophin receptor activity; nucleotide binding; protein binding; protein kinase activity; protein tyrosine kinase activity; receptor activity; transferase activity; transferase activity, transferring phosphorus-containing groups; transmembrane receptor protein tyrosine kinase activity |
Products Types
◆ Recombinant Protein | ||
NTRK3-2938R | Recombinant Rhesus Macaque NTRK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
NTRK3-159H | Active Recombinant Human NTRK3 protein(Met1-Asp428), His&hFc-tagged | +Inquiry |
Ntrk3-4524M | Recombinant Mouse Ntrk3 Protein, Myc/DDK-tagged | +Inquiry |
Ntrk3-009M | Recombinant Mouse Ntrk3 Protein, His-tagged | +Inquiry |
Ntrk3-625M | Recombinant Mouse Ntrk3 protein(Met1-Thr429), His-tagged | +Inquiry |
◆ Lysates | ||
NTRK3-2825HCL | Recombinant Human NTRK3 cell lysate | +Inquiry |
NTRK3-2583MCL | Recombinant Mouse NTRK3 cell lysate | +Inquiry |
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