Recombinant Mouse Ntrk3 Protein, His-tagged

• Cat.No.: Ntrk3-035M
• Product Overview: Recombinant mouse TrkC, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Description: Receptor tyrosine kinase involved in nervous system and probably heart development. Upon binding of its ligand NTF3/neurotrophin-3, NTRK3 autophosphorylates and activates different signaling pathways, including the phosphatidylinositol 3-kinase/AKT and the MAPK pathways, that control cell survival and differentiation.
• Source: Insect cells
• Species: Mouse
• Tag: His
• Form: Liquid
• Molecular Mass: 45.4 kDa
• AA Sequence: CPANCVCSKTEINCRRPDDGNLFPL LEGQDSGNSNGNASINITDISRNIT SIHIENWRGLHTLNAVDMELYTGLQ KLTIKNSGLRNIQPRAFAKNPHLRY INLSSNRLTTLSWQLFQTLSLRELR LEQNFFNCSCDIRWMQLWQEQGEAR LDSQSLYCISADGSQLPLFRMNISQ CDLPEISVSHVNLTVREGDNAVITC NGSGSPLPDVDWIVTGLQSINTHQT NLNWTNVHAINLTLVNVTSEDNGFT LTCIAENVVGMSNASVALTVYYPPR VVSLVEPEVRLEHCIEFVVRGNPTP TLHWLYNGQPLRESKIIHMDYYQEG EVSEGCLLFNKPTHYNNGNYTLIAK NALGTANQTINGHFLKEPFPESTDF FDFESDASPTPPITVTHKPEEDT
• Endotoxin: < 1 EU/μg of protein (determined by LAL method)
• Purity: > 90% by SDS-PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +2 to +8 centigrade for 1 week. For long term storage, aliquot and store at -20 to -114 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/mL (determined by Absorbance at 280nm)
• Storage Buffer: Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol

Gene Information

• Gene Name: Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 [ Mus musculus (house mouse) ]
• Official Symbol: Ntrk3
• Synonyms: Ntrk3; neurotrophic tyrosine kinase, receptor, type 3; Trk; TrkC; AW125844; Ntrk3_tv3; NT-3 growth factor receptor; GP145-TrkC; neurotrophin-3; trk-C; trkC tyrosine kinase; EC 2.7.10.1
• Gene ID: 18213
• mRNA Refseq: NM_008746
• Protein Refseq: NP_032772
• UniProt ID: Q6VNS1