Active Recombinant Human NTRK3 Protein, His-tagged
Cat.No. : | NTRK3-161H |
Product Overview : | Human TrkC / NTRK3 Protein (Human TrkC, His Tag) Cys 32 - Thr 429 (Accession # AAH13693.1) was produced in human 293 cells (HEK293). |
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Source : | HEK293 |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Cys 32 |
Form : | Lyophilized from sterile PBS, pH7.4, 10% Trehalose. |
Bio-activity : | Measured by its ability to inhibit NT-3-induced proliferation of BaF-TrkB-BD mouse pro-B cells transfected with TrkB. The ED50 for this effect is typically 0.01 - 0.1 ug/mL in the presence of 40 ng/mL of recombinant human NT-3. |
Molecular Mass : | Human TrkC, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 45.6 kDa. The reducing protein migrates as 80-90 kDa in SDS-PAGE due to glycosylation. |
Endotoxin : | Less than 1.0 EU per μg by the LAL method. |
Purity : | >95% as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Protein length : | Cys32-Thr429 |
Gene Name : | NTRK3 neurotrophic tyrosine kinase, receptor, type 3 [ Homo sapiens ] |
Official Symbol : | NTRK3 |
Synonyms : | NTRK3; neurotrophic tyrosine kinase, receptor, type 3; NT-3 growth factor receptor; TRKC; GP145-TrkC; ETV6-NTRK3 fusion; tyrosine kinase receptor C; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; gp145(trkC); |
Gene ID : | 4916 |
mRNA Refseq : | NM_001007156 |
Protein Refseq : | NP_001007157 |
MIM : | 191316 |
UniProt ID : | Q16288 |
Chromosome Location : | 15q24-q25 |
Pathway : | Neurotrophic factor-mediated Trk receptor signaling, organism-specific biosystem; Neurotrophin signaling pathway, organism-specific biosystem; Neurotrophin signaling pathway, conserved biosystem; |
Function : | ATP binding; neurotrophin binding; nucleotide binding; receptor activity; transmembrane receptor protein tyrosine kinase activity; |
Products Types
◆ Recombinant Protein | ||
NTRK3-159H | Active Recombinant Human NTRK3 protein(Met1-Asp428), His&hFc-tagged | +Inquiry |
Ntrk3-035M | Recombinant Mouse Ntrk3 Protein, His-tagged | +Inquiry |
Ntrk3-625M | Recombinant Mouse Ntrk3 protein(Met1-Thr429), His-tagged | +Inquiry |
NTRK3-3765R | Recombinant Rat NTRK3 Protein, His (Fc)-Avi-tagged | +Inquiry |
NTRK3-380H | Recombinant Human NTRK3 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
NTRK3-2583MCL | Recombinant Mouse NTRK3 cell lysate | +Inquiry |
NTRK3-2825HCL | Recombinant Human NTRK3 cell lysate | +Inquiry |
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Not For Human Consumption!
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