Recombinant Human Neurotrophic Tyrosine Kinase, Receptor, Type 3

• Cat.No.: NTRK3-497H

Specification

• Cat. No.: NTRK3-497H
• Description: Tropomyosin-related kinase C (TrkC) is a receptor for neurotrophins, a family of closely related proteins that are important physiological regulators of the survival of specific neurons within the peripheral nervous system (PNS) of vertebrates. TrkC specifically mediates biological responses to neurotrophin-3.
• Molecular Weight: The predicted molecular weight of Recombinant Human TrkC is Mr 72 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 130-150 kDa.
• Source: Mammalian cells
• State of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <0.1 ng per 1 µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20°C to -70℃. After aseptic reconstitution, this protein may be stored at 2°C to 8°C for one month or at -20°C to -70°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: NTRK3 neurotrophic tyrosine kinase, receptor, type 3 [ Homo sapiens ]
• Synonyms: NTRK3; neurotrophic tyrosine kinase, receptor, type 3; TRKC; gp145(trkC); ETV6-NTRK3 fusion; OTTHUMP00000192915; neurotrophin 3 receptor; tyrosine kinase receptor C; NT-3 growth factor receptor; ETS related protein-neurotrophic receptor tyrosine kinase fusion protein; EC 2.7.10.1; GP145-TrkC; OTTHUMP00000192915; Trk-C; Neurotrophic tyrosine kinase receptor type 3; TrkC tyrosine kinase
• Gene ID: 4916
• mRNA Refseq: NM_001007156
• Protein Refseq: NP_001007157
• MIM: 191316
• UniProt ID: Q16288
• Chromosome Location: 15q25
• Pathway: Neurotrophin signaling pathway
• Function: ATP binding; neurotrophin receptor activity; nucleotide binding; protein binding; transferase activity; transmembrane receptor protein tyrosine kinase activity