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Official Full Name platelet derived growth factor D
Background The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines, seven of which are found in this factor. This gene product only forms homodimers and, therefore, does not dimerize with the other three family members. It differs from alpha and beta members of this family in having an unusual N-terminal domain, the CUB domain. Two splice variants have been identified for this gene.
Synonyms PDGFD; platelet derived growth factor D; platelet-derived growth factor D; IEGF; MSTP036; SCDGF B; spinal cord derived growth factor B; PDGF-D; iris-expressed growth factor; spinal cord-derived growth factor B; spinal cord-derived growth factor-B; SCDGFB; SCDGF-B
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • CHO
    • E.coli
    • HEK293
    • Human Cell
    • Mammalian Cell
    • NS0
    • Tag :
    • His
    • SUMO
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PDGFD-1611H Recombinant Human PDGFD, His-tagged E.coli His
    Human PDGFD-207H Recombinant Human PDGFD, His tagged Human Cell His
    Human PDGFD-211H Recombinant Human PDGFD NS0 N/A
    Human PDGFD-24H Recombinant Human PDGFD protein CHO N/A
    Human PDGFD-3335HCL Recombinant Human PDGFD 293 Cell Lysate HEK293 N/A
    Human PDGFD-3336HCL Recombinant Human PDGFD 293 Cell Lysate HEK293 N/A
    Human PDGFD-7140H Recombinant Human Platelet Derived Growth Factor D, His-tagged E.coli His
    Mouse PDGFD-12569M Recombinant Mouse PDGFD Protein Mammalian Cell His
    Mouse Pdgfd-390M Recombinant Mouse Pdgfd protein, His/SUMO-tagged E.coli His/SUMO
    Rat PDGFD-4339R Recombinant Rat PDGFD Protein Mammalian Cell His
    Rat Pdgfd-8157R Recombinant Rat Pdgfd protein, His & T7-tagged E.coli His/T7
    Chicken PDGFD-5169C Recombinant Chicken PDGFD Mammalian Cell His

    pdgfd involved in several pathways and played different roles in them. We selected most pathways pdgfd participated on our site, such as Ras signaling pathway, Rap signaling pathway, Phospholipase D signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with pdgfd were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ras signaling pathway PAK3; ABL1; ETS1; INS2; RELA; GNB1; SHC2; KRAS; LOC608458; RRAS2
    Rap signaling pathway RAP1A; ITGA2B; BCAR1; MAGI1; RHOA; RASGRP3; PIK3R2; Fgf15; FGFR3; PRKD1
    Phospholipase D signaling pathway PIK3CG; AGTR1B; GNA12; GRM3; PDGFC; AGPAT4; PLA2G4F; FCER1G; RRAS2; AVPR2
    PIK-Akt signaling pathway FGF22; IFNA12; MAP2K1; INSR; RAF1; CREB3L1; FGF6; IFNA6; HGF; IL3
    Focal adhesion RHOB; ACTB2; FLNC; COL5A2; AKT2; COL6A4; SHC2; RAP1A; MAPK8A; ACTN3
    Regulation of actin cytoskeleton CDC42; PIP4K2C; GIT1; PAK2; SCINLA; FGF20B; FGF20; INS1; FGFR1A; PTK2
    Prostate cancer MAP4K1; IGF1; IKBKG; PTEN; SMARCA4; PDGFB; INS2; PIK3R2; NDRG1; PIK3R5
    Melanoma FGF1; FGF18; PIK3CD; FGFR1; HGF; MAP2K2; FGF5; PIK3CB; FGF9; MITF
    Choline metabolism in cancer WASF1; TAE1; MAPK1; SLC22A2; MAPK3; Pdgfa&Pdgfb; RAC3; RAC1; MAPK9; CHKA

    pdgfd has several biochemical functions, for example, growth factor activity, platelet-derived growth factor receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by pdgfd itself. We selected most functions pdgfd had, and list some proteins which have the same functions with pdgfd. You can find most of the proteins on our site.

    Function Related Protein
    growth factor activity FGF14; HDGF; FGF6; INHBAB; NDR2; PDGFC; GDF11; TGFA; LEP; SPAW
    platelet-derived growth factor receptor binding LYN; PDGFRA; PDGFRB; ITGA5; PDGFC; PDGFD; VEGFA; TYMP; PTEN; PDGFB

    pdgfd has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with pdgfd here. Most of them are supplied by our site. Hope this information will be useful for your research of pdgfd.

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