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Official Full Name SUMO/sentrin specific peptidase family member 8
Background This gene encodes a cysteine protease that is a member of the sentrin-specific protease family. The encoded protein is involved in processing and deconjugation of the ubiquitin-like protein termed, neural precursor cell expressed developmentally downregulated 8. Alternate splicing results in multiple transcript variants.
Synonyms SENP8; SUMO/sentrin specific peptidase family member 8; protease, cysteine, 2 (NEDD8 specific) , PRSC2, SUMO/sentrin specific protease family member 8; sentrin-specific protease 8; DEN1; deneddylase 1; HsT17512; NEDD8 specific protease 1; NEDP1; sentrin/
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SENP8-177H Recombinant Human SENP8, GST-tagged E.coli GST
    Human SENP8-1970HCL Recombinant Human SENP8 293 Cell Lysate HEK293 N/A
    Human SENP8-6271H Recombinant Human SENP8 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human SENP8-70H Recombinant Human SENP8, His-tagged E.coli His
    Human SENP8-829H Recombinant Human SENP8 Protein, His-tagged E.coli His
    Mouse SENP8-14884M Recombinant Mouse SENP8 Protein Mammalian Cell His
    Mouse Senp8-5764M Recombinant Mouse Senp8 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Rat SENP8-5319R Recombinant Rat SENP8 Protein Mammalian Cell His
    Rhesus Macaque SENP8-4140R Recombinant Rhesus monkey SENP8 Protein, His-tagged Mammalian Cell His
    Chicken SENP8-5549C Recombinant Chicken SENP8 Mammalian Cell His
    Zebrafish SENP8-4623Z Recombinant Zebrafish SENP8 Mammalian Cell His

    SENP8 involved in several pathways and played different roles in them. We selected most pathways SENP8 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with SENP8 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein

    SENP8 has several biochemical functions, for example, cysteine-type peptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SENP8 itself. We selected most functions SENP8 had, and list some proteins which have the same functions with SENP8. You can find most of the proteins on our site.

    Function Related Protein
    cysteine-type peptidase activity CAPN5A; CASP8L1; CTSC; CASP7; OTUD5A; CASP6L2; CTSSB.2; USP17L3; CTSZ; CTSL1B

    SENP8 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SENP8 here. Most of them are supplied by our site. Hope this information will be useful for your research of SENP8.

    RPL11; NEDD8

    Curtis, VF; Ehrentraut, SF; et al. Stabilization of HIF through inhibition of Cullin-2 neddylation is protective in mucosal inflammatory responses. FASEB JOURNAL 29:208-215(2015).
    Curtis, V; Ehrentraut, S; et al. Contribution of human deneddylase-1/SENP8 to the mucosal inflammatory response. FASEB JOURNAL 28:-(2014).

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