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  • Official Full Name


  • Overview

    Sialophorin (leukosialin) is a major sialoglycoprotein on the surface of human T lymphocytes, monocytes, granulocytes, and some B lymphocytes, which appears to be important for immune function and may be part of a physiologic ligand-receptor complex involved in T-cell activation.
  • Synonyms

    Leukosialin; GALGP; OTTHUMP00000123397; GPL115; OTTHUMP00000196610; sialophorin (leukosialin, CD43); sialophorin (gpL115, leukosialin, CD43); CD43 antigen; Leukocyte sialoglycoprotein; Galactoglycoprotein; LSN; CD43; SPN; sialophorin;

  • Recombinant Proteins
  • Others
  • Protein Pre-coupled Magnetic Beads
  • Cell & Tissue Lysates
  • Homo sapiens (Human)
  • Human
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • E. coli
  • E.coli
  • E.coli expression system
  • HEK293
  • HEK293T
  • Human
  • Human Cell
  • Mammalian cells
  • C
  • His
  • Fc
  • Flag
  • His (Fc)
  • Avi
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
  • GST
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human SPN-2310H Recombinant Human SPN, His-tagged E.coli His 257aa
Human SPN-4264H Recombinant Human Sialophorin Human N/A
Human SPN-6532H Recombinant Human SPN Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CDA088P Recombinant Human CD-43 E.coli N/A
Human SPN-2685H Recombinant Human SPN Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human SPN-1075HFL Recombinant Full Length Human SPN Protein, C-Flag-tagged Mammalian cells Flag
Human SPN-2663H Recombinant Human SPN protein(281-360 aa), C-His-tagged E. coli C-His 281-360 aa
Human SPN-3246H Recombinant Human SPN Protein, His-tagged E. coli His 20-253 aa
Human SPN-3521H Recombinant Human SPN protein, His-SUMO-tagged E.coli His-SUMO 20-253aa
Human SPN-2087H-B Recombinant Human SPN Protein Pre-coupled Magnetic Beads HEK293
Human SPN-2087H Recombinant Human SPN Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human SPN-6347H Recombinant Human SPN Protein (Ser20-Arg253), His tagged E.coli His Ser20-Arg253
Human SPN-5117H Recombinant Human SPN Protein (Met1-Arg253), C-His tagged Mammalian cells C-His Met1-Arg253
Mouse Spn-7035M Recombinant Mouse Spn, Fc tagged Human Cell Fc
Mouse SPN-1739MCL Recombinant Mouse SPN cell lysate Human Cell N/A
Mouse Spn-6102M Recombinant Mouse Spn Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Spn-7035MA Recombinant Mouse Spn protein, Fc-tagged, APC labeled HEK293 Fc
Mouse Spn-7035MAF488 Recombinant Mouse Spn Protein, Fc-tagged, Alexa Fluor 488 conjugated HEK293 Fc 470
Mouse Spn-7035MAF647 Recombinant Mouse Spn Protein, Fc-tagged, Alexa Fluor 647 conjugated HEK293 Fc 470
Mouse Spn-7035MAF555 Recombinant Mouse Spn Protein, Fc-tagged, Alexa Fluor 555 conjugated HEK293 Fc 470
Mouse Spn-7035MF Recombinant Mouse Spn Protein, Fc-tagged, FITC conjugated HEK293 Fc 470
Mouse Spn-2094M Recombinant Mouse Spn Protein, His&GST-tagged E.coli N-His&GST Asp20-Gly248
Mouse Spn-7035MP Recombinant Mouse Spn protein, Fc-tagged, R-PE labeled HEK293 Fc
Rat Spn-50R Recombinant Rat Spn, Fc tagged Human Cell His
Rat SPN-893RCL Recombinant Rat SPN cell lysate Human Cell N/A
Homo sapiens (Human) RFL9493HF Recombinant Full Length Human Leukosialin(Spn) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (20-400)
Mus musculus (Mouse) RFL26763MF Recombinant Full Length Mouse Leukosialin(Spn) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (20-395)
Rattus norvegicus (Rat) RFL36287RF Recombinant Full Length Rat Leukosialin(Spn) Protein, His-Tagged E.coli expression system His Full Length of Mature Protein (8-378)
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • SPN Related Articles
  • SPN Related Research Area

SPN involved in several pathways and played different roles in them. We selected most pathways SPN participated on our site, such as Cell adhesion molecules (CAMs), Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with SPN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Epstein-Barr virus infectionFCER2;HLA-F;TRADD;PIK3CD;PSMC6;CSNK2A2;PIK3R2;HLA-B;HLA-DQB1

SPN has several biochemical functions, for example, protein binding, transmembrane signaling receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SPN itself. We selected most functions SPN had, and list some proteins which have the same functions with SPN. You can find most of the proteins on our site.

Function Related Protein
transmembrane signaling receptor activityTLR4;TRPV1;GHRHRA;TNFRSF11A;KLRC2;FZD9B;GPR126;TLR2-2;MPL

SPN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SPN here. Most of them are supplied by our site. Hope this information will be useful for your research of SPN.


Liu, ZQ; Liu, Y; et al. Meet-in-the-middle fault analysis on word-oriented substitution-permutation network block ciphers. SECURITY AND COMMUNICATION NETWORKS 8:672-681(2015).
Yim, BS; Kim, JM; et al. Electrical and mechanical properties of multiwalled carbon nanotubes-reinforced solderable polymer nanocomposites. JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS 26:1678-1689(2015).
  • Q&As
  • Reviews

Q&As (7)

Ask a question
What is the primary role of SPN in immune cell function? 12/29/2022

SPN, or Sialophorin, is important in modulating the function of immune cells, particularly lymphocytes.

What potential therapeutic applications arise from targeting SPN in immune disorders? 12/28/2022

Targeting SPN could provide new treatment approaches for managing immune-related conditions, including autoimmune diseases.

How do genetic variations in SPN affect immune response? 07/10/2019

Genetic changes in SPN can lead to variations in immune cell behavior and effectiveness.

What role does SPN play in cell adhesion and migration? 12/12/2018

SPN plays a role in regulating immune cell adhesion and migration, crucial for immune surveillance and response.

How does SPN interact with other components of the immune system? 05/13/2018

SPN interacts with other immune molecules, coordinating immune cell communication and function.

What is the impact of altered SPN activity on autoimmune diseases? 02/12/2018

Altered SPN activity can impact the regulation of immune responses, potentially leading to autoimmune disorders.

How does SPN contribute to immune cell signaling? 08/11/2017

It contributes to immune cell signaling, influencing cell activation and response to stimuli.

Customer Reviews (3)

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