Recombinant Human SPN Protein, MYC/DDK-tagged
| Cat.No. : | SPN-2685H |
| Product Overview : | Recombinant Human SPN protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293. |
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| Description : | The protein encoded by this gene is a major sialoglycoprotein found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It may be part of a physiologic ligand-receptor complex involved in T-cell activation. During T-cell activation, this protein is actively removed from the T-cell-APC (antigen-presenting cell) contact site, suggesting a negative regulatory role in adaptive immune response |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Myc&DDK |
| Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Molecular Mass : | 40.1 kDa |
| Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : | >50 ug/mL as determined by microplate BCA method |
| Gene Name : | SPN sialophorin [ Homo sapiens ] |
| Official Symbol : | SPN |
| Synonyms : | CD43; GALGP; GPL115; LSN |
| Gene ID : | 6693 |
| mRNA Refseq : | NM_001030288 |
| Protein Refseq : | NP_001025459 |
| MIM : | 182160 |
| UniProt ID : | P16150 |
Products Types
| ◆ Recombinant Protein | ||
| Spn-2094M | Recombinant Mouse Spn Protein, His&GST-tagged | +Inquiry |
| SPN-2663H | Recombinant Human SPN protein(281-360 aa), C-His-tagged | +Inquiry |
| SPN-3246H | Recombinant Human SPN Protein, His-tagged | +Inquiry |
| SPN-2087H | Recombinant Human SPN Protein, His (Fc)-Avi-tagged | +Inquiry |
| Spn-7035M | Recombinant Mouse Spn protein(Met1-Gly248), hFc-tagged | +Inquiry |
| ◆ Lysates | ||
| SPN-1739MCL | Recombinant Mouse SPN cell lysate | +Inquiry |
| SPN-893RCL | Recombinant Rat SPN cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewAccurate and timely results, crucial for research progress.
Instrumental in our research achievements, highly trusted.
Efficient and dependable, aids our research significantly.
Q&As (7)
Ask a questionSPN, or Sialophorin, is important in modulating the function of immune cells, particularly lymphocytes.
Targeting SPN could provide new treatment approaches for managing immune-related conditions, including autoimmune diseases.
Genetic changes in SPN can lead to variations in immune cell behavior and effectiveness.
SPN plays a role in regulating immune cell adhesion and migration, crucial for immune surveillance and response.
SPN interacts with other immune molecules, coordinating immune cell communication and function.
Altered SPN activity can impact the regulation of immune responses, potentially leading to autoimmune disorders.
It contributes to immune cell signaling, influencing cell activation and response to stimuli.
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