Recombinant Full Length Human Leukosialin(Spn) Protein, His-Tagged

• Cat.No.: RFL9493HF
• Product Overview: Recombinant Full Length Human Leukosialin(SPN) Protein (P16150) (20-400aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E.coli expression system
• Species: Homo sapiens (Human)
• Tag: His
• Form: Lyophilized powder
• Protein length: Full Length of Mature Protein (20-400)
• AA Sequence: STTAVQTPTSGEPLVSTSEPLSSKM YTTSITSDPKADSTGDQTSALPPST SINEGSPLWTSIGASTGSPLPEPTT YQEVSIKMSSVPQETPHATSHPAVP ITANSLGSHTVTGGTITTNSPETSS RTSGAPVTTAASSLETSRGTSGPPL TMATVSLETSKGTSGPPVTMATDSL ETSTGTTGPPVTMTTGSLEPSSGAS GPQVSSVKLSTMMSPTTSTNASTVP FRNPDENSRGMLPVAVLVALLAVIV LVALLLLWRRRQKRRTGALVLSRGG KRNGVVDAWAGPAQVPEEGAVTVTV GGSGGDKGSGFPDGEGSSRRPTLTT FFGRRKSRQGSLAMEELKSGSGPSL KGEEEPLVASEDGAVDAPAPDEPEG GDGAAP
• Purity: Greater than 90% as determined by SDS-PAGE.
• Applications: SDS-PAGE
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Tris/PBS-based buffer, 6% Trehalose, pH 8.0
• Reconstitution: We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
• Gene Name: SPN
• Synonyms: CD 43; CD43; CD43 antigen; Galactoglycoprotein; GALGP; GPL 115; GPL115; Human gene for sialophorin ; Leucocyte sialoglycoprotein; LEUK_HUMAN; Leukocyte large sialoglycoprotein; Leukocyte sialoglycoprotein; Leukosialin; LSN; Ly-48; sialophorin (gpL115, leu
• UniProt ID: P16150

Gene Information

• Gene Name: SPN
• Synonyms: CD 43; CD43; CD43 antigen; Galactoglycoprotein; GALGP; GPL 115; GPL115; Human gene for sialophorin ; Leucocyte sialoglycoprotein; LEUK_HUMAN; Leukocyte large sialoglycoprotein; Leukocyte sialoglycoprotein; Leukosialin; LSN; Ly-48; sialophorin (gpL115, leu
• UniProt ID: P16150

Reviews

06/23/2023

Accurate and timely results, crucial for research progress.

10/02/2018

Instrumental in our research achievements, highly trusted.

03/26/2018

Efficient and dependable, aids our research significantly.

Q&As

What is the primary role of SPN in immune cell function?

SPN, or Sialophorin, is important in modulating the function of immune cells, particularly lymphocytes.

What potential therapeutic applications arise from targeting SPN in immune disorders?

Targeting SPN could provide new treatment approaches for managing immune-related conditions, including autoimmune diseases.

How do genetic variations in SPN affect immune response?

Genetic changes in SPN can lead to variations in immune cell behavior and effectiveness.

What role does SPN play in cell adhesion and migration?

SPN plays a role in regulating immune cell adhesion and migration, crucial for immune surveillance and response.

How does SPN interact with other components of the immune system?

SPN interacts with other immune molecules, coordinating immune cell communication and function.

What is the impact of altered SPN activity on autoimmune diseases?

Altered SPN activity can impact the regulation of immune responses, potentially leading to autoimmune disorders.

How does SPN contribute to immune cell signaling?

It contributes to immune cell signaling, influencing cell activation and response to stimuli.