Recombinant Mouse Spn Protein, Fc-tagged, Alexa Fluor 488 conjugated

• Cat.No.: Spn-7035MAF488
• Product Overview: Alexa Fluor 488 conjugated recombinant Mouse Spn (P15702) extracellular domain (Met 1-Gly 248), fused with the Fc region of human IgG1 at the C-terminus, was produced in Human Cell.

Specification

• Source: HEK293
• Species: Mouse
• Tag: Fc
• Form: Lyophilized
• Molecular Mass: The secreted recombinant mouse SPN/Fc is a disulfide-linked homodimer. The reduced monomer comprises 470 amino acids and has a calculated molecular mass of 49.6 kDa. As a result of glycosylation, the apparent molecular mass of rmSPN/Fc monomer is approximately 110 kDa in SDS-PAGE under reducing conditions.
• Protein length: 470
• Endotoxin: < 1.0 EU/ μg of the protein as determined by the LAL method.
• Characteristic: Disulfide-linked homodimer
  Labeled with Alexa Fluor 488 via amines
  Excitation Wavelength: 488 nm
  Emission Wavelength: 515­-545 nm
• Stability: Samples are stable for up to 12 months from date of receipt at -70 centigrade.
• Storage: Store it under sterile conditions at -20 to -70 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Lyophilized from sterile PBS, pH 7.4
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.

Gene Information

• Gene Name: Spn sialophorin [ Mus musculus ]
• Official Symbol: Spn
• Gene ID: 20737
• mRNA Refseq: NM_001037810
• Protein Refseq: NP_001032899

Reviews

06/23/2023

Accurate and timely results, crucial for research progress.

10/02/2018

Instrumental in our research achievements, highly trusted.

03/26/2018

Efficient and dependable, aids our research significantly.

Q&As

What is the primary role of SPN in immune cell function?

SPN, or Sialophorin, is important in modulating the function of immune cells, particularly lymphocytes.

What potential therapeutic applications arise from targeting SPN in immune disorders?

Targeting SPN could provide new treatment approaches for managing immune-related conditions, including autoimmune diseases.

How do genetic variations in SPN affect immune response?

Genetic changes in SPN can lead to variations in immune cell behavior and effectiveness.

What role does SPN play in cell adhesion and migration?

SPN plays a role in regulating immune cell adhesion and migration, crucial for immune surveillance and response.

How does SPN interact with other components of the immune system?

SPN interacts with other immune molecules, coordinating immune cell communication and function.

What is the impact of altered SPN activity on autoimmune diseases?

Altered SPN activity can impact the regulation of immune responses, potentially leading to autoimmune disorders.

How does SPN contribute to immune cell signaling?

It contributes to immune cell signaling, influencing cell activation and response to stimuli.