Recombinant Rat Spn protein(Met1-Gly243), hFc-tagged

Cat.No. : Spn-50R
Product Overview : Recombinant Rat SPN (NP_001258015.1)(Met1-Gly243) was expressed in HEK293 with the Fc region of Human IgG1 at the C-terminus.
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Source : HEK293
Species : Rat
Tag : C-hFc
Protein length : Met1-Gly243
Form : Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant rat SPN/Fc is a disulfide-linked homodimer. The reduced monomer comprises 465 amino acids and has a predicted molecular mass of 49.3 kDa. The apparent molecular mass of the protein is approximately 95, 57 and 50 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 95 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Spn sialophorin [ Rattus norvegicus ]
Official Symbol : Spn
Synonyms : SPN; sialophorin; leukosialin; Leukosialin; W3/13 antigen; leukocyte sialoglycoprotein; Sialophorin (gpL115, leukosianin, CD43); Lsn; Cd43; Lsn1; gpL115;
Gene ID : 24796

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (7)

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What is the primary role of SPN in immune cell function? 12/29/2022

SPN, or Sialophorin, is important in modulating the function of immune cells, particularly lymphocytes.

What potential therapeutic applications arise from targeting SPN in immune disorders? 12/28/2022

Targeting SPN could provide new treatment approaches for managing immune-related conditions, including autoimmune diseases.

How do genetic variations in SPN affect immune response? 07/10/2019

Genetic changes in SPN can lead to variations in immune cell behavior and effectiveness.

What role does SPN play in cell adhesion and migration? 12/12/2018

SPN plays a role in regulating immune cell adhesion and migration, crucial for immune surveillance and response.

How does SPN interact with other components of the immune system? 05/13/2018

SPN interacts with other immune molecules, coordinating immune cell communication and function.

What is the impact of altered SPN activity on autoimmune diseases? 02/12/2018

Altered SPN activity can impact the regulation of immune responses, potentially leading to autoimmune disorders.

How does SPN contribute to immune cell signaling? 08/11/2017

It contributes to immune cell signaling, influencing cell activation and response to stimuli.

Customer Reviews (3)

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06/23/2023

    Accurate and timely results, crucial for research progress.

    10/02/2018

      Instrumental in our research achievements, highly trusted.

      03/26/2018

        Efficient and dependable, aids our research significantly.

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