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Official Full Name SMT3 suppressor of mif two 3 homolog 2
Background This gene encodes a protein that is a member of the SUMO (small ubiquitin-like modifier) protein family. It functions in a manner similar to ubiquitin in that it is bound to target proteins as part of a post-translational modification system. However, unlike ubiquitin which targets proteins for degradation, this protein is involved in a variety of cellular processes, such as nuclear transport, transcriptional regulation, apoptosis, and protein stability. It is not active until the last two amino acids of the carboxy-terminus have been cleaved off. Numerous pseudogenes have been reported for this gene. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Synonyms SUMO2; SMT3 suppressor of mif two 3 homolog 2 (S. cerevisiae); SMT3 (suppressor of mif two 3, yeast) homolog 2 , SMT3 suppressor of mif two 3 homolog 2 (yeast) , SMT3H2; small ubiquitin-related modifier 2; SMT3B; sentrin 2; SMT3 homolog 2; ubiquitin-like
    • Species :
    • Chicken
    • Cynomolgus Monkey
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SUM02-13H Recombinant Human SUM02 E.coli N/A
    Human SUMO2-1722HCL Recombinant Human SUMO2 cell lysate N/A
    Human SUMO2-250H Recombinant Human SUMO2, His-tagged E.coli His
    Human SUMO2-28787TH Recombinant Human SUMO2 E.coli N/A
    Human SUMO2-2921H Recombinant Human SUMO2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Human SUMO2-3016H Recombinant Human SUMO2 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human SUMO2-432H Recombinant Human SUMO2 Protein, GST-tagged E.coli GST
    Human SUMO2-433H Recombinant Human SUMO2 Protein E.coli N/A
    Human SUMO2-435H Recombinant Human SUMO2 Protein, His-tagged E.coli His
    Human SUMO2-587H Recombinant Human SUMO2 E.coli N/A
    Human SUMO2-588H Recombinant Human SUMO2, His-tagged E.coli His
    Human SUMO2-590H Recombinant Human SUMO2 E.coli N/A
    Human SUMO2-591H Recombinant Human SUMO2 E.coli N/A
    Human SUMO2-592H Recombinant Human SUMO2 E.coli N/A
    Mouse SUMO2-16238M Recombinant Mouse SUMO2 Protein Mammalian Cell His
    Rat SUMO2-5840R Recombinant Rat SUMO2 Protein Mammalian Cell His
    Cynomolgus Monkey SUMO2-991C Recombinant Cynomolgus SUMO2 Protein, His-tagged Mammalian Cell His
    Rhesus Macaque SUMO2-4561R Recombinant Rhesus monkey SUMO2 Protein, His-tagged Mammalian Cell His
    Chicken SUMO2-3612C Recombinant Chicken SUMO2 Mammalian Cell His

    sumo2 involved in several pathways and played different roles in them. We selected most pathways sumo2 participated on our site, such as RNA transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with sumo2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    RNA transport THOC3; SRRM1; FMR1; SARNP; NUP188; NUP93; FXR1; EIF2S2; RBM8A; PABPC1

    sumo2 has several biochemical functions, for example, poly(A) RNA binding, protein binding, protein tag. Some of the functions are cooperated with other proteins, some of the functions could acted by sumo2 itself. We selected most functions sumo2 had, and list some proteins which have the same functions with sumo2. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding NONO; VCP; DDX39A; SFPQ; SOSTDC1B; MEX3C; EIF3C; GDI2; RPF2; MACF1
    protein binding MED14; RBMY1A1; F11R; OSTC; BIRC5; RPS6KB1; PLEKHM1; FAM184A; KLF12; TRP63
    protein tag RNF41; SUMO2B; SUMO3A; SUMO3; SUMO4; SUMO3B; NFATC2IP; SUMO2; SUMO1; UBL5
    ubiquitin protein ligase binding FLJ11011L; HSPA1A; NDUFS2; SMAD7; WASH; RELA; UBE2U; LYN; UBE2V1; NGFR

    sumo2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with sumo2 here. Most of them are supplied by our site. Hope this information will be useful for your research of sumo2.

    CHD3; PELP1; USPL1; uspl1; HOMEZ; SENP2; USP25

    Collaud, S; Tischler, V; et al. Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN. BMC CANCER 15:-(2015).
    Bund, T; Spoden, GA; et al. An L2 SUMO interacting motif is important for PML localization and infection of human papillomavirus type 16. CELLULAR MICROBIOLOGY 16:1179-1200(2014).

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