TANK

Official Full Name

TRAF family member-associated NFKB activator
Overview

A tank locomotive or tank engine is a steam locomotive that carries its water in one or more on-board water tanks, instead of pulling it behind it in a tender. It will most likely also have some kind of bunker (or oil tank) to hold the fuel. There are several different types of tank locomotive dependent upon the position and style of the water tanks and fuel bunkers. The most common type has tanks mounted either side of the boiler. This type originated about 1840 and quickly became popular for industrial tasks, and later for shunting and shorter distance main line duties. Tank locomotives have advantages and disadvantages compared to traditional tender locomotives.
Synonyms

TANK; TRAF family member-associated NFKB activator; TRAF2; I-TRAF; TRAF family member-associated NF-kappa-B activator; OTTHUMP00000162915; OTTHUMP00000200692; OTTHUMP00000200693; OTTHUMP00000200694; OTTHUMP00000200695; OTTHUMP00000200696; OTTHUMP00000200700; TRAF-interacting protein; I TRAF; TANK_HUMAN; TRAF family member associated NF KAPPA B activator; TRAF interacting protein; TRAF interacting protein TANK isoform a; TRAF interacting protein TANK isoform b; TRAF-interacting protein2; OTTHUMP00000200703; OTTHUMP00000200704; OTTHUMP00000200698; ITRAF;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell
Yeast

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	TANK-517H	Recombinant Human TANK	E.coli	Non		Inquiry
Human	TANK-31497TH	Recombinant Human TANK	E.coli	Non	1-119	Inquiry
Human	TANK-31443TH	Recombinant Human TANK	E.coli	Non	119 amino acids	Inquiry
Human	TANK-7244H	Recombinant Human TANK, His-tagged	E.coli	His	1-425aa	Inquiry
Human	TANK-1256HCL	Recombinant Human TANK 293 Cell Lysate	HEK293	Non		Inquiry
Human	TANK-3551H	Recombinant Human TANK protein, GST-tagged	E.coli	GST	1-119aa	Inquiry
Human	TANK-4997H	Recombinant Human TANK Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc&DDK		Inquiry
Human	TANK-1531H	Recombinant Human TANK Protein (1-119 aa), His-tagged	Yeast	His	1-119 aa	Inquiry
Human	TANK-5509H	Recombinant Human TANK Protein (Leu131-Ile369), N-His tagged	E.coli	His	Leu131-Ile369	Inquiry
Human	TANK-518H	Recombinant Human TANK protein, His-T7-tagged	E.coli	His&T7	Leu131~Ile369	Inquiry
Mouse	Tank-6289M	Recombinant Mouse Tank Protein, Myc/DDK-tagged	HEK293T	Myc&DDK		Inquiry
Rhesus Macaque	TANK-4615R	Recombinant Rhesus monkey TANK Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	TANK-4431R	Recombinant Rhesus Macaque TANK Protein, His (Fc)-Avi-tagged	HEK293	His&Fc&Avi		Inquiry
Rhesus Macaque	TANK-4431R-B	Recombinant Rhesus Macaque TANK Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	TANK-4496Z	Recombinant Zebrafish TANK	Mammalian Cell	His		Inquiry
Chicken	TANK-5214C	Recombinant Chicken TANK	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Other Resource
TANK Related Signal Pathway

TANK involved in several pathways and played different roles in them. We selected most pathways TANK participated on our site, such as Activated TLR4 signalling, Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon, Immune System, which may be useful for your reference. Also, other proteins which involved in the same pathway with TANK were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Activated TLR4 signalling	CHUK;DUSP7;RIPK3;S100A12;SIGIRR;S100B;DUSP6;TANK;PELI3
Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon	TANK;TICAM1
Immune System	CLEC2D;TRIM22;DEFB106A;HAVCR2;OASL;TREM1;BTLA;KLRG1;TRIM14
Innate Immune System	MYO1C;TRIM56;TLR6;PPAPDC1A;PELI3;TNIP2;NLRP4E;DEFA5;TXNIPB
MyD88-independent TLR3/TLR4 cascade	RIPK3;TANK
RIG-I-like receptor signaling pathway	AZI2;TBK1;CXCL10;MAP3K1;RNF207B;IKBKB;IFNA2;DDX3;IRF3
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways	TAX1BP1B;RNF216;PCBP2;NLRC5;HERC5;RNF135;TAX1BP1;TANK
TNF-alpha/NF-kB Signaling Pathway	SMARCC2;SMARCB1;CSNK2A1P;SMARCE1;NR2C2;USP2;MCC;CRADD;KPNA6

TANK has several biochemical functions, for example, metal ion binding, protein binding, ubiquitin protein ligase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by TANK itself. We selected most functions TANK had, and list some proteins which have the same functions with TANK. You can find most of the proteins on our site.

Function	Related Protein
metal ion binding	ZFAND5B;ZNF592;ZFP322A;CLCA4;ATP2B1B;ZNF174;ZBTB48;PHOSPHO2;ZNF335
protein binding	TMEM59;CRHBP;NARG2;CFL1;RNF168;HEY2;TUBB2A;TTC23L;BRD4
ubiquitin protein ligase binding	PRKACA;RAD18;SLC22A18;TRP53;UBE2V2;UBXN1;HM13;SUMO2;TMEM173

TANK has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with TANK here. Most of them are supplied by our site. Hope this information will be useful for your research of TANK.

TBK1; IKBKE; TRAF2; TRAF3

Gene Family

Research Area

Apoptosis Adaptor Proteins

NOD-like Receptors and the Inflammasome

RIG-I-like Receptors

Adaptor Proteins

Huang, HF; Zeng, Z; et al. Heme oxygenase-1 protects rat liver against warm ischemia/reperfusion injury via TLR2/TLR4-triggered signaling pathways. WORLD JOURNAL OF GASTROENTEROLOGY 21:2937-2948(2015).

Serrano-Perez, B; Almeria, S; et al. Coxiella burnetii total immunoglobulin G, phase I and phase II immunoglobulin G antibodies, and bacterial shedding in young dams in persistently infected dairy herds. JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION 27:167-176(2015).