| Description : |
The TRAF (tumor necrosis factor receptor-associated factor) family of proteins associate with and transduce signals from members of the tumor necrosis factor receptor superfamily. The protein encoded by this gene is found in the cytoplasm and can bind to TRAF1, TRAF2, or TRAF3, thereby inhibiting TRAF function by sequestering the TRAFs in a latent state in the cytoplasm. For example, the protein encoded by this gene can block TRAF2 binding to LMP1, the Epstein-Barr virus transforming protein, and inhibit LMP1-mediated NF-kappa-B activation. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
47.8 kDa |
| AA Sequence : |
MDKNIGEQLNKAYEAFRQACMDRDS AVKELQQKTENYEQRIREQQEQLSL QQTIIDKLKSQLLLVNSTQDNNYGC VPLLEDSETRKNNLTLDQPQDKVIS GIAREKLPKVRRQEVSSPRKETSAR SLGSPLLHERGNIEKTFWDLKEEFH KICMLAKAQKDHLSKLNIPDTATET QCSVPIQCTDKTDKQEALFKPQAKD DINRGAPSITSVTPRGLCRDEEDTS FESLSKFNVKFPPMDNDSTFLHSTP ERPGILSPATSEVVCQEKFNMEFRD NPGNFVKTEETLFEIQGIDPIASAI QNLKTTDKTKPSNLVNTCIRTTLDR AACLPPGDHNALYVNSFPLLDPSDA PFPSLDSPGKAIRGPQQPIWKPFPN QDSDSVVLSGTDSELHIPRVCEFCQ AVFPPSITSRGDFLRHLNSHFNGET TRTRPLEQKLISEEDLAANDILDYK DDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
