| Description : |
This gene encodes an extracellular matrix protein with a spatially and temporally restricted tissue distribution. This protein is homohexameric with disulfide-linked subunits, and contains multiple EGF-like and fibronectin type-III domains. It is implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity, and neuronal regeneration. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
240.91 kDa |
| AA Sequence : |
MGAMTQLLAGVFLAFLALATEGGVL KKVIRHKRQSGVNATLPEENQPVVF NHVYNIKLPVGSQCSVDLESASGEK DLAPPSEPSESFQEHTVDGENQIVF THRINIPRRACGCAAAPDVKELLSR LEELENLVSSLREQCTAGAGCCLQP ATGRLDTRPFCSGRGNFSTEGCGCV CEPGWKGPNCSEPECPGNCHLRGRC IDGQCICDDGFTGEDCSQLACPSDC NDQGKCVNGVCICFEGYAGADCSRE ICPVPCSEEHGTCVDGLCVCHDGFA GDDCNKPLCLNNCYNRGRCVENECV CDEGFTGEDCSELICPNDCFDRGRC INGTCYCEEGFTGEDCGKPTCPHAC HTQGRCEEGQCVCDEGFAGVDCSEK RCPADCHNRGRCVDGRCECDDGFTG ADCGELKCPNGCSGHGRCVNGQCVC DEGYTGEDCSQLRCPNDCHSRGRCV EGKCVCEQGFKGYDCSDMSCPNDCH QHGRCVNGMCVCDDGYTGEDCRDRQ CPRDCSNRGLCVDGQCVCEDGFTGP DCAELSCPNDCHGRGRCVNGQCVCH EGFMGKDCKEQRCPSDCHGQGRCVD GQCICHEGFTGLDCGQHSCPSDCNN LGQCVSGRCICNEGYSGEDCSEVSP PKDLVVTEVTEETVNLAWDNEMRVT EYLVVYTPTHEGGLEMQFRVPGDQT STIIRELEPGVEYFIRVFAILENKK SIPVSARVATYLPAPEGLKFKSIKE TSVEVEWDPLDIAFETWEIIFRNMN KEDEGEITKSLRRPETSYRQTGLAP GQEYEISLHIVKNNTRGPGLKRVTT TRLDAPSQIEVKDVTDTTALITWFK PLAEIDGIELTYGIKDVPGDRTTID LTEDENQYSIGNLKPDTEYEVSLIS RRGDMSSNPAKETFTTGLDAPRNLR RVSQTDNSITLEWRNGKAAIDSYRI KYAPISGGDHAEVDVPKSQQATTKT TLTGLRPGTEYGIGVSAVKEDKESN PATINAATELDTPKDLQVSETAETS LTLLWKTPLAKFDRYRLNYSLPTGQ WVGVQLPRNTTSYVLRGLEPGQEYN VLLTAEKGRHKSKPARVKASTEQAP ELENLTVTEVGWDGLRLNWTAADQA YEHFIIQVQEANKVEAARNLTVPGS LRAVDIPGLKAATPYTVSIYGVIQG YRTPVLSAEASTGETPNLGEVVVAE VGWDALKLNWTAPEGAYEYFFIQVQ EADTVEAAQNLTVPGGLRSTDLPGL KAATHYTITIRGVTQDFSTTPLSVE VLTEEVPDMGNLTVTEVSWDALRLN WTTPDGTYDQFTIQVQEADQVEEAH NLTVPGSLRSMEIPGLRAGTPYTVT LHGEVRGHSTRPLAVEVVTEDLPQL GDLAVSEVGWDGLRLNWTAADNAYE HFVIQVQEVNKVEAAQNLTLPGSLR AVDIPGLEAATPYRVSIYGVIRGYR TPVLSAEASTAKEPEIGNLNVSDIT PESFNLSWMATDGIFETFTIEIIDS NRLLETVEYNISGAERTAHISGLPP STDFIVYLSGLAPSIRTKTISATAT TEALPLLENLTISDINPYGFTVSWM ASENAFDSFLVTVVDSGKLLDPQEF TLSGTQRKLELRGLITGIGYEVMVS GFTQGHQTKPLRAEIVTEAEPEVDN LLVSDATPDGFRLSWTADEGVFDNF VLKIRDTKKQSEPLEITLLAPERTR DLTGLREATEYEIELYGISKGRRSQ TVSAIATTAMGSPKEVIFSDITENS ATVSWRAPTAQVESFRITYVPITGG TPSMVTVDGTKTQTRLVKLIPGVEY LVSIIAMKGFEESEPVSGSFTTALD GPSGLVTANITDSEALARWQPAIAT VDSYVISYTGEKVPEITRTVSGNTV EYALTDLEPATEYTLRIFAEKGPQK SSTITAKFTTDLDSPRDLTATEVQS ETALLTWRPPRASVTGYLLVYESVD GTVKEVIVGPDTTSYSLADLSPSTH YTAKIQALNGPLRSNMIQTIFTTIG LLYPFPKDCSQAMLNGDTTSGLYTI YLNGDKAQALEVFCDMTSDGGGWIV FLRRKNGRENFYQNWKAYAAGFGDR REEFWLGLDNLNKITAQGQYELRVD LRDHGETAFAVYDKFSVGDAKTRYK LKVEGYSGTAGDSMAYHNGRSFSTF DKDTDSAITNCALSYKGAFWYRNCH RVNLMGRYGDNNHSQGVNWFHWKGH EHSIQFAEMKLRPSNFRNLEGRRKR ATRTRPLEQKLISEEDLAANDILDY KDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
