Active Recombinant Human FGF10 Protein (169 aa)
Cat.No. : | FGF10-421F |
Product Overview : | Recombinant Human FGF-10 produced in E. coli is a single, non-glycosylated polypeptide chain containing 169 amino acids. A fully biologically active molecule, rhFGF-10 has a molecular mass of 19.3 kDa analyzed by reducing SDS-PAGE and is obtained by chromatographic techniques. |
- Specification
- Gene Information
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Description : | Fibroblast Growth Factor-10 (FGF-10) is a mitogen mainly produced by mesenchymal stem cells in the lung. FGF-10 belongs to the heparin binding FGF family, and is also known as Keratinocyte Growth Factor-2 (KGF-2). It shares homology with KGF and receptor binding to FGFR2-IIIb. However, while KGF induces proliferation and differentiation of various epithelial cells, FGF-10 promotes budding and branching morphogenesis during the multi-organ development via mesenchymal-epithelial cell interactions. FGF-10 is critical for lung and limb development, and is regulated by Shh during early development. |
Source : | E. coli |
Species : | Human |
Form : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Bio-activity : | ED50 < 20 ng/mL, measured by a cell proliferation assay using 4 MBr-5 cells, corresponding to a specific activity of > 5.0 × 10^4 units/mg. |
Molecular Mass : | 19.3 kDa, observed by reducing SDS-PAGE. |
Protein Length : | 169 |
AA Sequence : | LGQDMVSPEATNSSSSSFSSPSSAG RHVRSYNHLQGDVRWRKLFSFTKYF LKIEKNGKVSGTKKENCPYSILEIT SVEIGVVAVKAINSNYYLAMNKKGK LYGSKEFNNDCKLKERIEENGYNTY ASFNWQHNGRQMYVALNGKGAPRRG QKTRRKNTSAHFLPMVVHS |
Endotoxin : | < 0.2 EU/μg, determined by LAL method. |
Purity : | > 95% as analyzed by SDS-PAGE. |
Storage : | Lyophilized recombinant Human FGF-10 remains stable up to 6 months at -80 centigrade from date of receipt. Upon reconstitution, Human FGF-10 should be stable up to 1 week at 4 centigrade or up to 3 months at -20 centigrade. |
Storage Buffer : | Lyophilized after extensive dialysis against PBS. |
Reconstitution : | Reconstituted in ddH2O at 100 μg/mL. |
Gene Name : | FGF10 fibroblast growth factor 10 [ Homo sapiens ] |
Official Symbol : | FGF10 |
Synonyms : | FGF10; fibroblast growth factor 10; FGF-10; keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria; |
Gene ID : | 2255 |
mRNA Refseq : | NM_004465 |
Protein Refseq : | NP_004456 |
MIM : | 602115 |
UniProt ID : | O15520 |
Products Types
◆ Recombinant Protein | ||
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FGF10-088F | Active Recombinant Human FGF10 Protein (170 aa, 40-208) | +Inquiry |
FGF10-6262C | Recombinant Chicken FGF10 Protein, His tagged | +Inquiry |
FGF10-024H | Active Recombinant Human FGF10 Protein | +Inquiry |
◆ Lysates | ||
FGF10-6251HCL | Recombinant Human FGF10 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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