Active Recombinant Human FGF10 Protein

• Cat.No.: FGF10-4097H
• Product Overview: Human FGF10 (O15520, 1 a.a. - 208 a.a.) full-length recombinant protein expressed in Escherichia coli.

Specification

• Description: The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that this gene is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. This gene is also implicated to be a primary factor in the process of wound healing. [provided by RefSeq
• Source: E. coli
• Species: Human
• Form: Lyophilized
• Bio-activity: The ED50 was determined by the dose-dependent proliferation of BaF3 cells expressing FGF receptors, and was found to be <0.5 ng/mL., corresponding to a specific activity of 2.0 x 106 units/mg.
• Molecular Mass: 19 kDa
• AA Sequence: MWKWILTHCASAFPHLPGCCCCCFL LLFLVSSVPVTCQALGQDMVSPEAT NSSSSSFSSPSSAGRHVRSYNHLQG DVRWRKLFSFTKYFLKIEKNGKVSG TKKENCPYSILEITSVEIGVVAVKA INSNYYLAMNKKGKLYGSKEFNNDC KLKERIEENGYNTYASFNWQHNGRQ MYVALNGKGAPRRGQKTRRKNTSAH FLPMVVHS
• Endotoxin: < 0.1 ng/μg (1 EU/μg)
• Purity: > 90% by SDS-PAGE and HPLC
• Applications: Functional Study
  SDS-PAGE
• Storage: Store at -20 centigrade on dry atmosphere for 2 years. After reconstitution with deionized water, store at 4 centigrade for 1 month or store at -20 centigrade for 6 months. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: Lyophilized from PBS, pH 7.0
• Tag: Non

Gene Information

• Gene Name: FGF10 fibroblast growth factor 10 [ Homo sapiens ]
• Official Symbol: FGF10
• Synonyms: FGF10; fibroblast growth factor 10; FGF-10; keratinocyte growth factor 2; produced by fibroblasts of urinary bladder lamina propria
• Gene ID: 2255
• mRNA Refseq: NM_004465
• Protein Refseq: NP_004456
• MIM: 602115
• UniProt ID: O15520