Active Recombinant Human FLT3LG Protein, Pre-aliquoted

Cat.No. : FLT3LG-23H
Product Overview : Recombinant Human FLT3LG Protein, Thr27-Pro185, was expressed in Insect cell.
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Description : Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3LG controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 (see MIM 186910)-positive classical DCs and their CD103 (ITGAE; MIM 604682)-positive tissue counterparts (summary by Sathaliyawala et al., 2010 [PubMed 20933441]).
Source : Insect cell
Species : Human
Bio-activity : Measured in a cell proliferation assay using BaF3 mouse pro‑B cells transfected with mouse Flt-3. The ED50 for this effect is 0.2-1 ng/mL.
Molecular Mass : Predicted Molecular Mass:17.5 kDa
SDS-PAGE: 17-30 kDa, reducing conditions
Protein length : Thr27-Pro185
N-terminal Sequence Analysis : Thr27
Endotoxin : < 0.10 EU/μg of the protein by the LAL method.
Purity : > 97% by SDS-PAGE under reducing conditions and visualized by silver stain.
Stability : Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
• 6 months from date of receipt at room temperature as supplied.
• 12 months from date of receipt at 2-8 centigrade as supplied.
• 1 month at 2-8 centigrade under sterile conditions after reconstitution.
• 3 months at -20 to -80 centigrade under sterile conditions after reconstitution.
Reconstitution : For a stock solution, reconstitute at 100 μg/mL in sterile PBS, or simply roll Pre-aliquoted directly into cell culture medium for immediate use.
Shipping : The product is shipped at ambient temperature.
Gene Name : FLT3LG fms related receptor tyrosine kinase 3 ligand [ Homo sapiens (human) ]
Official Symbol : FLT3LG
Synonyms : FLT3LG; fms related receptor tyrosine kinase 3 ligand; FL; FLG3L; FLT3L; fms-related tyrosine kinase 3 ligand; flt3 ligand; fms related tyrosine kinase 3 ligand
Gene ID : 2323
mRNA Refseq : NM_001459
Protein Refseq : NP_001450
MIM : 600007
UniProt ID : P49771

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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