Active Recombinant Human Iinterleukin 23, Alpha Subunit P19
| Cat.No. : | L23A-269H |
| Product Overview : | Recombinant Human IL23A is expressed inHuman 293 cellsas a heterodimeric glycoprotein composed of two disulfide-linked subunits (p40 cystine linked to p19). |
- Specification
- Gene Information
- Related Products
| Cat. No. : | L23A-269H |
| Description : | Production in Human 293 cells offers authentic glycosylation. Cytokines produced in Sf9 or Sf21 cells have posttranslational modifications which are not humanlike. This gene encodes a subunit of the heterodimeric cytokine interleukin 23 (IL23). IL23 is composed of this protein and the p40 subunit of interleukin 12 (IL12B). The receptor of IL23 is formed by the beta 1 subunit of IL12 (IL12RB1) and an IL23 specific subunit, IL23R. Both IL23 and IL12 can activate the transcription activator STAT4, and stimulate the production of interferon-gamma (IFNG). In contrast to IL12, which acts mainly on naive CD4 (+) T cells, IL23 preferentially acts on memory CD4 (+) T cells. |
| Source : | Human 293 cells. |
| Endotoxin : | Endotoxin-free. |
| Purity : | >95%. The protein was resolved by SDS polyacrylamide gel electrophoresis and the gelwas stained with Coomassie blue. |
| Activity : | The specific activity was determined by the dose-dependent secretion of IL-17 from mouse splenocytes activated with 10ng/mL PMA. |
| Solubility : | It is recommended to reconstitute the lyophilized Bone Morphogenetic Protein-6 in sterile 20mM AcOH (acetic Acid) not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
| Storage : | -20℃. |
| Gene Name : | IL23A interleukin 23, alpha subunit p19 [Homo sapiens] |
| Synonyms : | P19; SGRF; IL-23; IL-23A; IL23P19; MGC79388; IL23A ;interleukin-23 subunit alpha ; IL-23-A ; IL-23p19 ; IL-23 subunit alpha ; interleukin 23 p19 subunit ; interleukin-23 subunit p19 ; JKA3 induced upon T-cell activation |
| Gene ID : | 51561 |
| mRNA Refseq : | NM_ 016584 |
| Protein Refseq : | NP_057668 |
| MIM : | 605580 |
| UniProt ID : | Q9NPF7 |
| Chromosome Location : | 12q13.3 |
| Pathway : | Cytokine-cytokine receptor interaction; Jak-STAT signaling pathway |
| Function : | cytokine activity; protein binding |
Products Types
| ◆ Recombinant Protein | ||
| IL23A-244H | Active Recombinant Human IL23A Protein (Arg20-Pro189), N-His tagged, Animal-free, Carrier-free | +Inquiry |
| IL23A-05H | Active Recombinant Human IL-23 Protein | +Inquiry |
| Il23A-23H | Recombinant Human Il23A&IL12B Protein, His-tagged | +Inquiry |
| IL23A-179H | Recombinant Active Human IL23A Protein, His-tagged(N-ter) | +Inquiry |
| Il23a-1927M | Recombinant Mouse Il23a Protein | +Inquiry |
| ◆ Lysates | ||
| IL23A-5231HCL | Recombinant Human IL23A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (1)
Ask a question
Is this bioactive cyno IL-23 heterodimer (p19/p40) or just the cyno IL-23p19 subunit?
02/01/2023
Please inquiry our product manager with specific product.
Ask a Question for All IL23A Products
Required fields are marked with *
My Review for All IL23A Products
Required fields are marked with *
0
Inquiry Basket
