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Active Recombinant Human IL1A Protein

Cat.No. : IL1A-02H
Product Overview : Recombinant Human IL1A Protein (Ser113-Ala271) without tag was exoressed in E. coli.
  • Specification
  • Gene Information
  • Related Products
Description : The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.
Source : E. coli
Species : Human
Bio-activity : Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. Symons, J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 272. The ED50 for this effect is 1‑6 pg/mL.
Molecular Mass : 18 kDa
Protein length : 13-271
N-terminal Sequence Analysis : Ser113
Endotoxin : < 0.10 EU/μg of the protein by the LAL method.
Purity : > 97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Storage : Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 centigrade as supplied.
1 month, 2 to 8 centigrade under sterile conditions after reconstitution.
3 months, -20 to -70 centigrade under sterile conditions after reconstitution.
Storage Buffer : Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution : Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping : The product is shipped at ambient temperature.
Gene Name : IL1A interleukin 1 alpha [ Homo sapiens (human) ]
Official Symbol : IL1A
Synonyms : IL1A; interleukin 1 alpha; IL1; IL-1A; IL1F1; IL1-ALPHA; IL-1 alpha; interleukin-1 alpha; hematopoietin-1; preinterleukin 1 alpha; pro-interleukin-1-alpha
Gene ID : 3552
mRNA Refseq : NM_000575
Protein Refseq : NP_000566
MIM : 147760
UniProt ID : P01583

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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