Recombinant Human IL20 Protein

• Cat.No.: IL20-160H
• Product Overview: Recombinant Human IL20 Protein without tag was expressed in E. coli.

Specification

• Description: Interleukin 20 (IL-20) is structurally related to interleukin 10 (IL-10) and is produced by keratinocytes and monocytes. IL-20 acts through the STAT3 signaling pathway to regulate the proliferation of keratinocytes during epidermal inflammation.
• Source: E. coli
• Species: Human
• Bio-activity: No biological activity data is available at this time.
• Molecular Mass: Dimer, 17.7/35.3 kDa (153/306 aa)
• AA Sequence: MLKTLNLGSCVIATNLQEIRNGFSE IRGSVQAKDGNIDIRILRRTESLQD TKPANRCCLLRHLLRLYLDRVFKNY QTPDHYTLRKISSLANSFLTIKKDL RLCHAHMTCHCGEEAMKKYSQILSH FEKLEPQAAVVKALGELDILLQWME ETE
• Endotoxin: ≤1 EUs/μg, Kinetic LAL
• Purity: ≥95%, Reducing and Non-Reducing SDS PAGE
• Stability: 12 months from date of receipt when stored at -20 to -80 centigrade as supplied.
  1 month when stored at 4 centigrade after reconstituting as directed.
  3 months when stored at -20 to -80 centigrade after reconstituting as directed.
• Storage: Storage Prior to Reconstitution: -20 centigrade
• Storage Buffer: Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, 20 mM sodium chloride, pH 7.5
• Reconstitution: Sterile water at 0.1 mg/mL
• Shipping: Room temperature
• Instructions: Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80 centigrade and avoid repeat freeze thaws.

Gene Information

• Gene Name: IL20 interleukin 20 [ Homo sapiens (human) ]
• Official Symbol: IL20
• Synonyms: IL20; interleukin 20; interleukin-20; IL 20; IL10D; ZCYTO10; cytokine Zcyto10; four alpha helix cytokine; IL-20; MGC96907
• Gene ID: 50604
• mRNA Refseq: NM_018724
• Protein Refseq: NP_061194
• MIM: 605619
• UniProt ID: Q9NYY1

Reviews

04/14/2023

The reliability and reproducibility of the IL20 Protein's performance make it a go-to option for WB experiments.

12/13/2022

The IL20 protein is of exceptional quality and will undoubtedly meet my experimental needs with utmost reliability and accuracy.

06/25/2021

By utilizing the IL20 protein in my experiments, I can trust that I am working with a product of the highest caliber, backed by a company dedicated to delivering exceptional quality and support.

Q&As

How does IL-20 influence tissue repair and regeneration?

IL-20 has been implicated in tissue repair processes, and harnessing its properties may have implications for regenerative medicine.

How is IL-20 protein clinically applied in treating autoimmune diseases?

IL-20 is being explored as a potential therapeutic target in autoimmune diseases due to its involvement in immune system regulation.

In what ways does IL-20 contribute to inflammatory responses?

IL-20 is known to promote inflammation, and understanding its mechanisms may lead to targeted anti-inflammatory therapies.

Are there any ongoing clinical trials involving IL-20 protein?

Yes, there are several clinical trials exploring the safety and efficacy of IL-20 inhibitors in various disease contexts.

Can IL-20 be a target for personalized medicine in autoimmune conditions?

Tailoring treatments based on individual IL-20 levels and responses is a potential avenue for personalized medicine.