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Recombinant Human IL20, StrepII-tagged

Cat.No. : IL20-268H
Product Overview : Purified, full-length human recombinant IL20 protein (amino acids 34-179, 146 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 17.5 kDa. (Accession NP_061194.2; UniProt Q9NYY1)
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  • Gene Information
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Description : IL20 is a cytokine structurally related to IL10. This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
Source : Human Cells
Species : Human
Tag : StrepII
Form : Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free).
Protein length : 34-179, 146 a.a.
AA Sequence : MAALQKSVSSFLMGTLATSCLLLLA LLVQGGAAAPISSHCRLDKSNFQQP YITNRTFMLAKEASLADNNTDVRLI GEKLFHGVSMSERCYLMKQVLNFTL EEVLFPQSDRFQPYMQEVVPFLARL SNRLSTCHIEGDDLHIQRNVQKLKD TVKKLGESGEIKAIGELDLLFMSLR NACI
Endotoxin : <0.1 eu per ug protein by lal
Purity : >80~80%% by SDS-PAGE
Storage : 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles.
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml.
Gene Name : IL20 interleukin 20 [ Homo sapiens ]
Official Symbol : IL20
Synonyms : IL20; interleukin 20; interleukin-20; IL 20; IL10D; ZCYTO10; cytokine Zcyto10; four alpha helix cytokine; IL-20; MGC96907;
Gene ID : 50604
mRNA Refseq : NM_018724
Protein Refseq : NP_061194
MIM : 605619
UniProt ID : Q9NYY1
Chromosome Location : 1q32
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function : cytokine activity; interleukin-20 receptor binding; receptor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does IL-20 influence tissue repair and regeneration? 03/20/2022

IL-20 has been implicated in tissue repair processes, and harnessing its properties may have implications for regenerative medicine.

How is IL-20 protein clinically applied in treating autoimmune diseases? 01/12/2022

IL-20 is being explored as a potential therapeutic target in autoimmune diseases due to its involvement in immune system regulation.

In what ways does IL-20 contribute to inflammatory responses? 08/01/2020

IL-20 is known to promote inflammation, and understanding its mechanisms may lead to targeted anti-inflammatory therapies.

Are there any ongoing clinical trials involving IL-20 protein? 03/21/2019

Yes, there are several clinical trials exploring the safety and efficacy of IL-20 inhibitors in various disease contexts.

Can IL-20 be a target for personalized medicine in autoimmune conditions? 01/17/2016

Tailoring treatments based on individual IL-20 levels and responses is a potential avenue for personalized medicine.

Customer Reviews (3)

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Reviews
04/14/2023

    The reliability and reproducibility of the IL20 Protein's performance make it a go-to option for WB experiments.

    12/13/2022

      The IL20 protein is of exceptional quality and will undoubtedly meet my experimental needs with utmost reliability and accuracy.

      06/25/2021

        By utilizing the IL20 protein in my experiments, I can trust that I am working with a product of the highest caliber, backed by a company dedicated to delivering exceptional quality and support.

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