Recombinant Human IL20, StrepII-tagged
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Cat.No. : | IL20-268H Optional Service: Optional requirements on this protein |
Product Overview : | Purified, full-length human recombinant IL20 protein (amino acids 34-179, 146 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 17.5 kDa. (Accession NP_061194.2; UniProt Q9NYY1) |
Description : | IL20 is a cytokine structurally related to IL10. This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. |
Source : | Human Cells |
Species : | Human |
Tag : | StrepII |
Form : | Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free). |
Protein length : | 34-179, 146 a.a. |
AA Sequence : | MAALQKSVSS FLMGTLATSC LLLLALLVQG GAAAPISSHC RLDKSNFQQP YITNRTFMLA KEASLADNNT DVRLI GEKLFHGVSM SERCYLMKQV LNFTLEEVLF PQSDRFQPYM QEVVPFLARL SNRLSTCHIE GDDLHIQRNV QKLKD TVKKLGESGE IKAIGELDLL FMSLRNACI |
Endotoxin : | <0.1 eu per ug protein by lal |
Purity : | >80~80%% by SDS-PAGE |
Storage : | 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles. |
Reconstitution : | Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. |
Gene Name : | IL20 interleukin 20 [ Homo sapiens ] |
Official Symbol : | IL20 |
Synonyms : | IL20; interleukin 20; interleukin-20; IL 20; IL10D; ZCYTO10; cytokine Zcyto10; four alpha helix cytokine; IL-20; MGC96907; |
Gene ID : | 50604 |
mRNA Refseq : | NM_018724 |
Protein Refseq : | NP_061194 |
MIM : | 605619 |
UniProt ID : | Q9NYY1 |
Chromosome Location : | 1q32 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
Function : | cytokine activity; interleukin-20 receptor binding; receptor binding; |
◆ Recombinant Protein
IL20-1818M | Recombinant Mouse IL20 Protein | +Inquiry |
Il20-173M | Recombinant Active Mouse IL20 Protein, His-tagged(C-ter) | +Inquiry |
Il20-3509M | Recombinant Mouse Il20 Protein | +Inquiry |
IL20-1028H | Recombinant Horse IL20 Protein, His-tagged | +Inquiry |
IL20-172H | Recombinant Active Human IL20 Protein, His-tagged(C-ter) | +Inquiry |
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◆ Lysates
IL20-5233HCL | Recombinant Human IL20 293 Cell Lysate | +Inquiry |
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IL10IL10RAIL10RBIL11IL11RAIl11ra1IL12IL12AIL12BIL12RB1IL13IL13RA1IL13RA2IL15IL15RAIL16IL17AIL17BIl17cIL17DIl17fIL17RAIL17RDIL18IL18BPIL18R1IL18RAPIl19Il1aIl1bIL1F10IL1R1Il1r2IL1RAPIL1RAPL1IL1RAPL2IL1RL1IL1RL2Il1rnIL2Il20IL20RAIL21IL21RIL22IL22BPIL22RA1IL22RA2IL23AIL24Il25IL27IL27RAIL28AIl28bIL29IL2RAIL2RBIl2rgIL3IL31IL32Il33Il34IL3RAIL4IL4RIl4raIl5IL5RAIl6IL6RIl6raIL6STIl7IL7RIL8IL9IL36AIl12rb2IL17RBIL23RIL26IL31RAIL36BIL36GIL36RNIL37IL9RIL17RCIL17REIL28RAIL4I1IL20RBIL17RELIl11ra2IL27bIL7RAIl23a&Il12b
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