Recombinant Human IL20, StrepII-tagged IL20-268H

Recombinant Human IL20, StrepII-tagged

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Cat.No. : IL20-268H Optional Service: Optional requirements on this protein
Product Overview : Purified, full-length human recombinant IL20 protein (amino acids 34-179, 146 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 17.5 kDa. (Accession NP_061194.2; UniProt Q9NYY1)
Description : IL20 is a cytokine structurally related to IL10. This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
Source : Human Cells
Species : Human
Tag : StrepII
Form : Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free).
Protein length : 34-179, 146 a.a.
AA Sequence : MAALQKSVSS FLMGTLATSC LLLLALLVQG GAAAPISSHC RLDKSNFQQP YITNRTFMLA KEASLADNNT DVRLI GEKLFHGVSM SERCYLMKQV LNFTLEEVLF PQSDRFQPYM QEVVPFLARL SNRLSTCHIE GDDLHIQRNV QKLKD TVKKLGESGE IKAIGELDLL FMSLRNACI
Endotoxin : <0.1 eu per ug protein by lal
Purity : >80~80%% by SDS-PAGE
Storage : 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles.
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml.
Gene Name : IL20 interleukin 20 [ Homo sapiens ]
Official Symbol : IL20
Synonyms : IL20; interleukin 20; interleukin-20; IL 20; IL10D; ZCYTO10; cytokine Zcyto10; four alpha helix cytokine; IL-20; MGC96907;
Gene ID : 50604
mRNA Refseq : NM_018724
Protein Refseq : NP_061194
MIM : 605619
UniProt ID : Q9NYY1
Chromosome Location : 1q32
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem;
Function : cytokine activity; interleukin-20 receptor binding; receptor binding;
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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