Recombinant Human LTA Protein, His/Flag/StrepII-tagged

• Cat.No.: LTA-4599H
• Product Overview: Purified LTA (AAH34729.1 58 a.a. - 205 a.a.) human recombinant protein with His-Flag-StrepII tag at N-terminus expressed in human cells.

Specification

• Description: The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis
• Source: Human cells
• Species: Human
• Tag: His/Flag/StrepII
• Form: Liquid
• Bio-activity: Not Tested
• Molecular Mass: 21.56 kDa
• AA Sequence: HSTLKPAAHLIGDPSKQNSLLWRAN TDRAFLQDGFSLSNNSLLVPTSGIY FVYSQVVFSGKAYSPKATSSPLYLA HEVQLFSSQYPFHVPLLSSQKMVYP GLQEPWLHSMYHGAAFQLTQGDQLS THTDGIPHLVLSPSTVFFGAFAL
• Applications: Western Blot
  Enzyme-linked Immunoabsorbent Assay
  SDS-PAGE
  Protein Interaction
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Concentration: ≥ 10 μg/mL
• Storage Buffer: 100 mM Tris-HCl pH 8.0, 150 mM NaCl, 1 mM EDTA, and 5 mM desthiobiotin.

Gene Information

• Gene Name: LTA lymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ]
• Official Symbol: LTA
• Synonyms: LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; LT-alpha; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1
• Gene ID: 4049
• mRNA Refseq: NM_000595
• Protein Refseq: NP_000586
• MIM: 153440
• UniProt ID: P01374

Reviews

04/14/2020

Its purity, integrity, and functionality are ensured through stringent quality control measures, which instills confidence in the reliability and accuracy of my research results.

01/03/2020

Their technical expertise, product quality, customer support, and supply management collectively contribute to the success and progress of my trials.

08/24/2017

The manufacturer also offers valuable customer support, actively aiding researchers in their experimental journey.

Q&As

What are some potential therapeutic applications of LTA protein?

LTA protein is being investigated for its potential use in cancer therapy, autoimmune diseases, and infectious diseases.

Are there any clinical trials involving LTA protein?

Clinical trials may have been initiated to investigate the therapeutic potential of LTA protein since my last update. It's advisable to check the latest information.

What are some potential side effects or adverse reactions associated with LTA protein therapy?

Potential side effects may include immune-related adverse events, such as inflammation and cytokine release syndrome.

Can LTA protein be used to treat autoimmune diseases?

LTA protein has been studied for its potential to modulate autoimmune responses, but more research is needed.

Can LTA protein be used in cancer treatment?

LTA protein has shown potential in cancer immunotherapy by targeting and destroying cancer cells.