Recombinant Human LTA, His-tagged
| Cat.No. : | LTA-31534TH |
| Product Overview : | RecombinantHumanTNF-beta, expressed in (BTI-Tn-5B1-4) High-5 Insect Cells. This is an 18.6 kDa protein containing 172 amino acid residues. (Due to glycosylation, TNF-beta has an approximate molecular weight of 19.3 kDa.) |
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| Species : | Human |
| Tag : | His |
| Description : | The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis. |
| Conjugation : | HIS |
| Form : | Lyophilised:Centrifuge the vial prior to opening.Reconstitute in water to a concentration of °C for 1 week or -20°C for future use. |
| Purity : | >95% by SDS-PAGE |
| Storage buffer : | Preservative: NoneEndotoxin level is less than 0.1 ng per μg (1EU/μg). |
| Storage : | Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. |
| Sequences of amino acids : | GVGLTPSAAQ TARQHPKMHL AHSTLKPAAH LIGDPSKQNS LLWRANTDRA FLQDGFSLSN NSLLVPTSGI YFVYSQVVFS GKAYSPKATS SPLYLAHEVQ LFSSQYPFHV PLLSSQKMVY PGLQEPWLHS MYHGAAFQLT QGDQLSTHTD GIPHLVLSPS TVFFGAFAL |
| Sequence Similarities : | Belongs to the tumor necrosis factor family. |
| Gene Name | LTA lymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ] |
| Official Symbol | LTA |
| Synonyms | LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; |
| Gene ID | 4049 |
| mRNA Refseq | NM_000595 |
| Protein Refseq | NP_000586 |
| MIM | 153440 |
| Uniprot ID | P01374 |
| Chromosome Location | 6p21.3 |
| Pathway | Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; |
| Function | cytokine activity; receptor binding; tumor necrosis factor receptor binding; |
Not For Human Consumption!
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