Active Recombinant Human LTA protein, His-tagged
| Cat.No. : | LTA-311H |
| Product Overview : | Active Recombinant Human LTA protein(P01374)(36~205 aa), fused with N-terminal His tag, was expressed in E.coli. |
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| Species : | Human |
| Source : | E.coli |
| Tag : | His |
| Protein Length : | 36-205 aa |
| Form : | Lyophilized from sterile PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300. |
| Bio-activity : | TNF-β, a member of the tumor necrosis factor family, is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells. The biological effects of TNF-β are very similar to TNF-α, due to the similarity of molecular structure and the receptors. As reported, TNF-β could inhibit the proliferation and induce necrosis of A549 cells, and the concentration of IL-1β in cell supernatant will increase after stimulation. Therefore, A549 cells were incubated in DMEM with TNF-β (10ng/mL) for 8h, 24h, 48h, 72h, then cells were observed by inverted microscope and IL-1β was detected in the cell supernatant by ELISA . |
| Molecular Mass : | 22.2kDa |
| Endotoxin : | <1.0EU per 1μg (determined by the LAL method). |
| Purity : | > 97% as determined by SDS-PAGE. |
| Storage : | Avoid repeated freeze/thaw cycles. Store at -20°C for 12 months. Aliquot and store at -80°C for 12 months. |
| Reconstitution : | Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
| Gene Name | LTA lymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ] |
| Official Symbol | LTA |
| Synonyms | LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1; LT-alpha; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1; |
| Gene ID | 4049 |
| mRNA Refseq | NM_000595 |
| Protein Refseq | NP_000586 |
| MIM | 153440 |
| UniProt ID | P01374 |
| ◆ Recombinant Proteins | ||
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| ◆ Native Proteins | ||
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| ◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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