Active Recombinant Mouse Chemokine (C-X-C Motif) Ligand 9, HIgG1 Fc-tagged

Cat.No. : CXCL9-346H
Product Overview : The extracellular domain of human CXCL9 (AAH63122.1)(Thr23-Thr125) is fused to the N-terminus of the Fc region of human IgG1 was expressed in CHO celL
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Description : The function of this gene has not been specifically defined; however, it is thought to be involved in T cell trafficking. This gene has been localized to 4q21 with INP10, which is also a member of the chemokine family of cytokines.?
Source : CHO cells
Species : Human
Tag : HIgG1 Fc-tagged
Form : Lyophilized from 0.2μm-filtered solution in PBS.
Bio-activity : Measured by its ability to chemoattract BaF3 mouse pro-B cells.
Molecular Mass : 38KDa (monomer)
AA Sequence : Thr23-Thr125
Endotoxin : <0.06 eu/μg as determined by lal>
Purity : >98%, by SDS-PAGE under reducing conditions.
Stability : Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.
Reconstitution : Reconstitute at 100μg/ml in sterile PBS.
Warning : Avoid freeze/thaw cycles.
Gene Name : CXCL9 chemokine (C-X-C motif) ligand 9 [ Homo sapiens ]
Official Symbol : CXCL9
Synonyms : CXCL9; chemokine (C-X-C motif) ligand 9; CMK, MIG, monokine induced by gamma interferon; C-X-C motif chemokine 9; crg 10; Humig; SCYB9; small-inducible cytokine B9; gamma-interferon-induced monokine; monokine induced by gamma interferon; monokine induced by interferon-gamma; CMK; MIG; crg-10;
Gene ID : 4283
mRNA Refseq : NM_002416
Protein Refseq : NP_002407
MIM : 601704
UniProt ID : Q07325
Chromosome Location : 4q21
Pathway : CXCR3-mediated signaling events, organism-specific biosystem; Chemokine receptors bind chemokines, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem;
Function : chemokine activity; cytokine activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What is the relationship between CXCL9 and the chemokine receptor CXCR3? 08/16/2022

CXCL9 can bind specifically to CXCR3 and accumulate at sites of inflammation, thereby inducing and exacerbating the inflammatory response.

Do you offer CXCL9 fused with other tags? 01/25/2022

Yes, we will provide you with the most suitable labels according to your experimental needs.

Can CXCL9 be detected in lymphoid tissue under normal physiological conditions? 11/23/2020

No, CXCL9 can only be detected when the organism is inflamed or infected.

CXCL9 is secreted by which cells? 11/21/2020

CXCL9 is mainly secreted by endothelial cells and monocytes.

What diseases has CXCL9 been closely associated with the study of? 10/19/2020

CXCL9 has been linked to pulmonary embolism, asthma and breast cancer research.

Customer Reviews (2)

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Reviews
02/21/2023

    Customer service promptly feedback my requests, technical staff timely solve the problems that arise.

    04/01/2022

      The protein composition was stable and the concentration was high, which allowed me to obtain satisfactory experimental results.

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