CXCL9
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Official Full Name
chemokine (C-X-C motif) ligand 9 -
Overview
MIG, also known as mig-1, CXCL9, is a member of the alpha subfamily of inflammatory chemokine. It is inducible in macrophages, hepatocytes, and endothelial cells by IFN-gamma, but not by TNF-alpha or bacterial lipopolysacchrides (LPS). Mig functions as a -
Synonyms
CXCL9;chemokine (C-X-C motif) ligand 9;C-X-C motif chemokine 9;M119;protein m119;small-inducible cytokine B9;gamma interferon-induced monokine;gamma-interferon-induced monokine;monokine induced by gamma interferon;monokine induced by interferon-gamma;small inducible cytokine B subfamily (Cys-X-Cys), member 9;CMK;Mig;MuMIG;Scyb9;crg-10;BB139920
Recombinant Proteins
- Human
- Rabbit
- Cynomolgus
- Mouse
- Rhesus macaque
- Bovine
- Equine
- Rat
- Feline
- Ovine
- Porcine
- Pig
- E.coli
- Yeast
- CHO
- HEK293
- Mammalian Cells
- Wheat Germ
- Human Cells
- In Vitro Cell Free System
- Non
- His
- Fc
- GST
- T7
- Flag
- Avi
- Myc
- SUMO
Involved Pathway
CXCL9 involved in several pathways and played different roles in them. We selected most pathways CXCL9 participated on our site, such as Cytokine-cytokine receptor interaction,Chemokine signaling pathway,Toll-like receptor signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with CXCL9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Cytokine-cytokine receptor interaction | TNFRSF10D,CCL1,VEGFAA,IFNA10,CRLF2,IL22RA2,IRX1,CCR5,EPO,IL12A |
| Chemokine signaling pathway | LOC100033925,SRC,CXCL14,PRKCD,CCL19,CXCR4,CXCL8,GNG5,PLCB3,CXCR3 |
| Toll-like receptor signaling pathway | MAP2K7,IFNAR2,CXCL10,TLR4,MAP2K2A,IL1B,AKT2L,PIK3CD,CASP8,IL6 |
Protein Function
CXCL9 has several biochemical functions, for example, CXCR3 chemokine receptor binding,chemokine activity,cytokine activity. Some of the functions are cooperated with other proteins, some of the functions could acted by CXCL9 itself. We selected most functions CXCL9 had, and list some proteins which have the same functions with CXCL9. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| CXCR3 chemokine receptor binding | CXCL11.8,CXCL11,CXCL10,PF4,CXCL13 |
| chemokine activity | CCL2,CXCL3,CCL28,PF4,Cxcl15,CCL19A.1,PPBP,XCL1,CCL25B,CXCL19 |
| protein binding | IQCB1,THRB,ZBTB26,TTC30B,RABEP1,DLG4,ZC3H18,ACAA2,FGF12,ACTL6A |
| cytokine activity | C1QTNF4,IL33,IL17D,LEFTY1,NAMPT,GM13279,Ifna11,LFT2,CSF1,INHBE |
Interacting Protein
CXCL9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with CXCL9 here. Most of them are supplied by our site. Hope this information will be useful for your research of CXCL9.
DPP4;SFTPC;PTPN5;SYNE4;CCDC155;PAX8;BMF
Resources
Research Area
Inflammatory MediatorsCytokines and Growth Factors Secreted by VSMC
Macrophage Markers
CXC Chemokines
Glioma Biomarkers
Related Services
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References
- Ma, T; Xu, JC; et al. Combination of C-X-C motif chemokine 9 and C-X-C motif chemokine 10 antibodies with FTY720 prolongs the survival of cardiac retransplantation allografts in a mouse model. EXPERIMENTAL AND THERAPEUTIC MEDICINE 9:1006-1012(2015).
- Poplawska-Kita, A; Kosciuszko-Zdrodowska, M; et al. High Serum IgG4 Concentrations in Patients with Hashimoto's Thyroiditis. INTERNATIONAL JOURNAL OF ENDOCRINOLOGY :-(2015).
